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首页> 外文期刊>Chemosensors >One-Step Polylactic Acid Screen-Printing Microfluidic Paper-Based Analytical Device: Application for Simultaneous Detection of Nitrite and Nitrate in Food Samples
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One-Step Polylactic Acid Screen-Printing Microfluidic Paper-Based Analytical Device: Application for Simultaneous Detection of Nitrite and Nitrate in Food Samples

机译：一步聚乳酸丝网印刷微流体纸分析装置：用于同时检测食品样品中亚硝酸盐和硝酸盐的应用

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摘要

In this work, we report a one-step approach for fabricating screened-printed microfluidic paper-based analytical devices (μPADs) using polylactic acid as a new hydrophobic material. A polylactic acid solution was screen printed onto chromatography papers to create hydrophobic patterns for fluidic channels. The optimal polylactic acid concentration for successful device fabrication is 9% w/v. The μPADs were fabricated within 2 min and provided high reproducibility and stability. The utility of polylactic acid screen-printing was demonstrated for the simultaneous detection of nitrite and nitrate using colorimetric detection. Under optimized experimental conditions, the detection limits and the linear ranges, respectively, were 1.2 mg L ?1 and 2–10 mg L ?1 for nitrite and 3.6 mg L ?1 and 10–50 mg L ?1 for nitrate. The detection times for both ions were found to be within 12 min. The developed μPAD was applied for the simultaneous determination of these ions in food samples, and no significant differences in the analytical results were observed compared to those of the reference method. The polylactic acid screen-printing approach presented here provides a simple, rapid, and cost-effective alternative fabrication method for fabricating μPADs.
机译：在这项工作中，我们报告了一种使用聚乳酸作为一种新的疏水材料来制造筛选印刷的微流体纸基分析装置（μPAD）的一步方法。将聚乳酸溶液印在色谱纸上，以产生流体通道的疏水图案。成功的装置制造的最佳聚乳酸浓度为9％w / v。 μPAD在2分钟内制造，提供高再现性和稳定性。用比色检测同时检测聚乳酸丝网印刷的效用，用于同时检测亚硝酸盐和硝酸盐。在优化的实验条件下，分别检测限值和线性范围为亚硝酸盐的1.2mg，1和2-10mgL≥1，3.6mg L 1和10-50mg L 2硝酸盐。发现两个离子的检测时间在12分钟内。施用的μPAD被应用于同时测定食物样品中的这些离子，与参考方法的那些相比，观察到分析结果的显着差异。这里提出的聚乳酸丝网印刷方法提供了一种用于制造μPAD的简单，快速和经济有效的替代制造方法。

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