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首页> 外文期刊>Circulation journal >Coronary Microvascular Dysfunction in Asymptomatic Patients Affected by Systemic Sclerosis　– Limited vs. Diffuse Form –
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Coronary Microvascular Dysfunction in Asymptomatic Patients Affected by Systemic Sclerosis　– Limited vs. Diffuse Form –

机译：受系统硬化症影响的无症状患者的冠状动脉微血管功能障碍 - LIMITED VS.

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Background: This observational study was designed to evaluate the prevalence of coronary microvascular dysfunction (CMD) in asymptomatic patients affected by systemic sclerosis (SSc), stratifying the results according to the limited (lcSSc) and the diffuse (dcSSc) forms of the disease. Methods?and?Results: We enrolled 19 consecutive asymptomatic patients with dcSSc (n=7) or lcSSc (n=12). In all subjects, coronary flow reserve (CFR) was assessed by measuring diastolic coronary flow velocities in the left anterior descending artery by pulsed wave Doppler at baseline and after dipyridamole infusion (0.84 mg·kg?1·6 min?1). Wall motion score index was evaluated at baseline and during stress. We enrolled 20 healthy subjects as controls. Mean CFR was 1.96±0.62 in patients and 2.69±0.47 in controls (P
机译：背景：该观察性研究旨在评估受系统硬化症（SSC）影响的无症状患者中冠状动脉微血管功能障碍（CMD）的患病率，根据有限（LCSSC）和疾病的弥漫性（DCSSC）形式的结果分层结果。方法？结果：我们注册了19例连续无症状的DCSSC（n = 7）或LCSSC（n = 12）。在所有受试者中，通过在基线下通过脉冲波多普勒测量左前后下降动脉的舒张冠状动脉速度来评估冠状动脉流量储备（CFR），并在双吡酰胺输注后（0.84mg·kg ·1·1最小？1 ）。在基线和压力期间评估墙壁运动分数索引。我们将20个健康受试者注册为控制。患者的平均CFR为1.96±0.62，对照组2.69±0.47（P

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