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首页> 外文期刊>Case Reports in Nephrology >The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus
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The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus

机译：患有全身狼疮红斑狼疮的患者中的各种形式的肾病综合征

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Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-old Caucasian female with an established diagnosis of SLE, who presented four times with new onset of proteinuria during a follow-up time of ten years, since the diagnosis of SLE. Specifically, she experienced two episodes of lupus membranous nephropathy, and after she achieved remission, she developed twice overt nephrotic syndrome associated with new and biopsy proven lupus podocytopathy. All these episodes of nephrotic syndrome were combined with systemic symptoms, attributed to lupus itself, while serological activity of lupus was also noted. This case highlights the importance of performing a kidney biopsy in all patients with SLE who have new renal manifestations, including nephrotic proteinuria.
机译：肾脏受累在系统性狼疮红斑（SLE）的患者中经常出现，尽管它可能不会出现疾病发作。关于临床和/或实验室表现的组合和/或严重程度，肾狼疮本身具有高度异质。这是一个45岁的白种人女性的案例，其诊断为SLE，他在十年后的后续时间内呈现出新的蛋白尿开始呈现了四次，因为诊断为SLE。具体而言，她经历了两种狼疮膜肾病，并且在她取得缓解后，她开发了两次与新的肾病综合征，与新的和活检验证的狼疮诗状病变相关。所有这些肾病综合征的情节都与系统性症状相结合，归因于狼疮本身，而狼疮的血清活动也被注意到。这种情况强调，在所有患有新的肾脏表现的患者中表演肾脏活检的重要性，包括肾病蛋白尿。

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