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首页> 外文期刊>BMC Nephrology >Papulonodular mucinosis, Guillain-Barré syndrome and nephrotic syndrome in a patient with systemic lupus erythematosus: a case report
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Papulonodular mucinosis, Guillain-Barré syndrome and nephrotic syndrome in a patient with systemic lupus erythematosus: a case report

机译：系统性红斑狼疮患者的papulonodular粘菌病，Guillain-Barré综合征和肾病综合征：病例报告

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Background Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients. Case presentation A 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed acute Guillain-Barré syndrome and class V lupus nephritis 2?years later. His cutaneous nodules had not been idententified for 2?years and were resected by surgical procedures twice until SLE was diagnosed. The kidney biopsy revealed class V lupus nephritis. The patient responded well to a short course of intravenous immunoglobulins and his muscle strength almost completely recovered. So far, he has undergone five cycles of cyclophosphamide combined with hydroxychloroquine and tapering prednisone, resulting in partial remission of lupus nephritis and disappearance of hypocomplementemia. Conclusion We reported a rare case of male patient with SLE with manifestation of class V lupus nephritis, Guillain-Barré syndrome and papulonodular mucinosis.
机译：背景技术了解系统性红斑狼疮（SLE）临床表现的频谱，尤其是罕见的变化，对于患者的诊断和有效管理至关重要。病例介绍一名26岁的中国SLE男性在2年后最初表现出皮肤丘疹性粘液病并发展为急性Guillain-Barré综合征和V级狼疮性肾炎。他的皮肤结节已经2年没有被发现，并且被外科手术切除了两次直到诊断出SLE。肾脏活检显示V类狼疮肾炎。病人对静脉注射免疫球蛋白短疗程反应良好，肌肉力量几乎完全恢复。到目前为止，他经历了五个周期的环磷酰胺联合羟氯喹和逐渐减少的泼尼松，导致狼疮性肾炎的部分缓解和低补体血症的消失。结论我们报告了一例罕见的男性SLE患者，其表现为V级狼疮性肾炎，格林-巴利综合征和丘疹性黏液病。

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