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首页> 外文期刊>Journal of drugs in dermatology: JDD >Papulonodular mucinosis in a patient with systemic lupus erythematosus and antiphospholipid syndrome
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Papulonodular mucinosis in a patient with systemic lupus erythematosus and antiphospholipid syndrome

机译:系统性红斑狼疮和抗磷脂综合征患者的睑环粘液病

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摘要

The skin is one of the target organs most commonly affected in lupus erythematosus (LE) and a wide range of cutaneous changes have been described in LE patients. Papulonodular mucinosis (PNM) in particular is an uncommon cutaneous manifestation of LE. We discuss the case of a 26-year-old Senegalese woman with systemic LE and antiphospholipid syndrome (APS) who presented with pruritic papules on her back and extremities that appeared when she was on vacation in Africa and non-compliant with medications. Histopathologic examination was consistent with PNM. The patient was treated with mycophenolate mofetil and hydroxychloroquine, with subjective relief in pruritis at 6-week follow-up. To our knowledge, this is the first case of PNM presenting in a patient with both SLE and APS. Whether APS contributes to the pathogenesis of PNM is currently unknown.
机译:皮肤是红斑狼疮(LE)最常见的靶器官之一,在LE患者中已描述了多种皮肤变化。丘脑粘液病(PNM)特别是LE的罕见皮肤表现。我们讨论了一个患有系统性LE和抗磷脂综合征(APS)的26岁塞内加尔妇女的情况,她在非洲度假时出现背部和四肢瘙痒性丘疹并且不服药。组织病理学检查与PNM一致。该患者接受了霉酚酸酯和羟氯喹治疗,在6周的随访中主观缓解了瘙痒症。据我们所知,这是患有SLE和APS的患者出现PNM的第一例。目前尚不清楚APS是否有助于PNM的发病机理。

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