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An Unusual Cause of Fetal Stroke: Secondary HSV Infection

机译:一种不寻常的胎儿卒中原因:继发性HSV感染

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Herpes simplex virus (HSV) is a recognized cause of neonatal infection, with hematologic vertical spread usually only during a primary infection. This is an unusual case with hematologic spread of an HSV 2 infection resulting in a fetal stroke, not associated with a primary outbreak during pregnancy. A 25-year-old multigravida at 26 weeks was diagnosed with a large fetal stroke. Previous ultrasounds showed normal anatomy. She had preterm labor and delivery, with unsuccessful neonatal resuscitation. Vesicular lesions were noted on the infant. Both the lesions and the cerebral spinal fluid were positive for HSV 2. She had documented HSV infection prior to pregnancy, indicating that this was due to a hematologic secondary infection, as there was no rupture of membranes or evidence of other modes of transmission. This case shows that, while unusual, HSV hematologic vertical transmission can occur in both primary and secondary infection during pregnancy. Infection screening is worthwhile in unexplained fetal strokes.
机译:疱疹病毒(HSV)是新生儿感染的公认原因,通常仅在原发性感染期间血液学垂直扩散。这是一种不寻常的情况,具有HSV 2感染的血液学扩散,导致胎儿中风,与妊娠期间的主要爆发无关。 26周的25岁的多里拉瓦拉有26周的胎儿中风。以前的超声波显示了正常的解剖学。她有早产和交付,新生儿复苏不成功。在婴儿上注意到凹凸病变。病变和脑脊髓均为HSV 2。她在怀孕之前记录了HSV感染,表明这是由于血液学继发感染,因为没有破裂的膜或其他传播方式的证据。这种情况表明,虽然在妊娠期间初级和二次感染中可能发生HSV血液学垂直变速而异。在未解释的胎儿中风中感染筛查是值得的。

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