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A Case of Trousseau’s Syndrome Accompanying Ovarian Cancer with Widespread Thromboembolisms

机译:围攻卵巢癌的Trousseau综合征,具有普遍的血栓栓塞

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The patient was a 41-year-old woman, gravida 0. She had no notable medical history. Laparoscopic right salpingo-oophorectomy and left cystectomy were performed for bilateral ovarian endometriomas, which were both pathologically diagnosed as benign. Six months later, she presented with left lower abdominal pain and expressive aphasia. Examination revealed multiple cerebral infarctions and pulmonary embolism. The patient was diagnosed with Trousseau’s syndrome secondary to ovarian cancer, and anticoagulant therapy was initiated. Despite treatment, she developed visual field loss due to occlusion of the left retinal artery; dizziness due to cerebellar infarction and myocardial infarction; and right hemiplegia due to new cerebral infarction. She received chemotherapy (two courses of paclitaxel and carboplatin), which did not improve her condition, and died two months after onset. An autopsy revealed that her left ovary was enlarged to a size of 12?cm and an endometrioid carcinoma G2 was identified. Ovarian cancer had spread throughout the abdominal cavity, and a large amount of pleural and ascites fluid was present. Multiple thrombi were found in bilateral pulmonary arteries and bilateral common iliac veins. There was a 2.5?cm thrombus in the left ventricle apex, and the anterior descending branch was obstructed by thrombus with recanalization.
机译:患者是一个41岁的女性,Gravida 0.她没有明显的病史。对双侧卵巢子宫内膜异构瘤进行腹腔镜右唾液管切除术和左膀胱切除术,其在病理学上诊断为良性。六个月后,她呈现出左下腹痛和表达性厌食症。检查显示多种脑梗塞和肺栓塞。患者被诊断患有Trouseau的综合征,继发于卵巢癌,并开始抗凝治疗。尽管治疗,但由于左视网膜动脉的闭塞,她开发了视野损失;由于小脑梗死和心肌梗塞引起的头晕;由于新的脑梗死,右偏瘫。她接受了化疗(两种疗程的紫杉醇和卡铂),这并没有改善她的病症,并在发病后两个月死亡。尸检显示,她的左卵巢被扩大到12℃的尺寸和鉴定子宫内甲状腺癌G2。卵巢癌在整个腹腔中涂布,存在大量的胸腔和腹水流体。在双侧肺动脉和双侧常见的髂静脉中发现多个血栓。左心室顶点中有2.5厘米的血栓,前下降分支被血栓阻塞,重新化。

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