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首页> 外文期刊>African Journal of Biotechnology >Distribution of red blood cell antigens in drug-resistant and drug-sensitive pulmonary tuberculosis
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Distribution of red blood cell antigens in drug-resistant and drug-sensitive pulmonary tuberculosis

机译：红细胞抗原在耐药性和药物敏感肺结核中的分布

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Tuberculosis (TB) is still a widespread world infectious disease.?Mycobacterium tuberculosis?kills more people than any other single pathogen, with an estimated one-third of the world's population being infected. According to the World Health Organization (WHO), two billion people are infected with the causative?bacillus?ofMycobacterium tuberculosis. Tuberculosis is rather prevalent in the country of Georgia today. Frequency distribution of ABO, Rh-Hr, MN, Kell blood group system antigens were studied in 277 TB patients (151-drug-sensitive and 126 drug-resistant) of pulmonary tuberculosis to know whether there was any association between them, and also between drug resistance and sensitiveness. They were compared with 485 healthy subjects. Tests were carried out by standard test-tube technique and plate reaction for the following antigens: A, B; C, c, D, E, e; K and k, M and N. The research materials were collected from Tuberculosis and Lung Diseases National Centre of Georgia and Ptisio-pulmonogical Hospital of Adjara Region (Georgia). Present serological study has shown high frequency distribution of 0 and B phenotypes and r allele from ABO system, D antigen from Rh-Hr system and M antigen from MN blood group in TB patients then healthy subjects. This might explain the sensitivity of these antigens with pulmonary tuberculosis in Georgia. No significant difference between drug resistant and drug sensitive TB was found, thus the research in this direction has no importance. No association existed even when divided by age group in incidence of pulmonary tuberculosis.
机译：结核病（TB）仍然是一个广泛的世界传染病。肺结核术治疗，比任何其他单一病原体杀死更多人，估计世界人口的三分之一被感染。根据世界卫生组织（世卫组织）的说法，有20亿人感染了造成的疾病？芽孢杆菌？肺结核术。今天在格鲁吉亚国家的结核病相当普遍。在277型TB患者（151-药物敏感和126抗毒性）的肺结核中，研究了ABO，Rh-HR，Mn，Kell血型系统抗原的频率分布，以了解它们之间是否存在任何关联，而且耐药性和敏感性。与485个健康科目进行比较。通过标准试管技术和板式反应进行试验，用于以下抗原：A，B; C，C，D，E，E; K和K，M和N.研究资料是从结核病和肺部疾病的佐治亚州和Ptisio-Pulinical医院（格鲁吉亚）的肺病疾病。目前血清学研究表明，来自ABO系统的0和B表型和R等位基因的高频分布，来自RH-HR系统的D抗原和来自TB患者的MN血液组的M抗原然后是健康的受试者。这可能解释了这些抗原与格鲁吉亚肺结核的敏感性。发现耐药性和药物敏感结核病之间没有显着差异，因此该方向的研究没有重要。即使在肺结核发病率的年龄组除以年龄组时也不存在。

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