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首页> 外文期刊>African Journal of Biotechnology >Ameliorative effect of glucomannan-containing yeast product (Mycosorb) and sodium bentonite on performance and antibody titers against Newcastle disease in broilers during chronic aflatoxicosis
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Ameliorative effect of glucomannan-containing yeast product (Mycosorb) and sodium bentonite on performance and antibody titers against Newcastle disease in broilers during chronic aflatoxicosis

机译：含有葡甘露霉甘油胺的酵母产品（MycOSObs）和膨润土对慢性毒性病变的肉鸡的性能和抗体滴度的改善作用

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The aim of this study was to determine the?impact?of?aflatoxin (AF), yeast glucomannan?(YG) and sodium bentonite?(SB)?on?performance and?immunization against Newcastle disease (ND) in broiler feed with naturally contaminated diet with aflatoxin.?For this experiment,?300?7-day-old Ross 308-strain broiler chickens werechosen and randomly assigned to ten dietary?treatments?in three replicates of ten chicks. Treatments were: 1)?diet free from aflatoxin (positive control group); 2) naturally contaminated diet with aflatoxin?(negative control group); 3, 4, 5, 6, 7, 8, 9 and 10) naturally contaminated diet with aflatoxin supplemented with 1.5% SB, 3% SB, 0.05% YG, 0.1% YG, 1.5% SB + 0.05% YG, 1.5% SB + 0.1% YG, 3% SB + 0.05% YG and 3% SB + 0.1% YG, respectively. Chicken in each replicate were weighed weekly and?feed intake, weight gain?and?feed conversion ratio weremeasured. Blood sample was taken from each bird and the titers of antibody against ND were measured by haemagglutination inhibition test.?Aflatoxin in contaminated diet was measured and confirmed by thin layer chromatography (TLC) to be 250 ppb.Compared to the?positive?control diet, growth parameters were significantly (P<0.05) lower in 250 ppb aflatoxin fed chicks during?experiment and also the antibody titer against ND was significantly (P<0.05) lower in?the?negative?control diet?from 35 to 42 days of age.?The addition of?yeast glucomannan?and sodium bentonite, individually and in combination to the AF-containing diet ameliorated the adverse effects of aflatoxin, but 0.1%?yeast glucomannan?supplementation to the contaminated diet with aflatoxin proved to be much more effective in the amelioration of the adverse effect of AF on performance and humeral immunity against ND.?Key word:?Aflatoxin, broilers, 0.1% yeast glucomannan, performance, Newcastle disease.
机译：这项研究的目的是确定？影响？α-黄曲霉毒素（AF），酵母葡糖胺？（YG）和膨润土钠？（SB）？性能和β造成肉鸡（ND）的免疫，自然污染的饮食与黄曲霉毒素。这个实验，？300？7日龄罗斯308-菌株肉鸡鸡，随机分配到十个膳食？治疗？在十只小鸡的三个重复中。治疗方法是：1）？无毒素的饮食（阳性对照组）; 2）与黄曲霉毒素自然污染的饮食？（阴性对照组）; 3,4,5,6,7,8,9和10）天然污染的饮食与黄曲霉毒素补充有1.5％Sb，3％Sb，0.05％Yg，0.1％Yg，1.5％Sb + 0.05％YG，1.5％SB + 0.1％yg，3％Sb + 0.05％yg和3％Sb + 0.1％yg。每周重复的鸡肉每周称重，然后进食，体重增加？和送料转换比。从每只鸟取出血液样品，通过血红素凝集抑制试验测量抗体的抗体的滴度。通过薄层色谱（TLC）测量污染饮食中的污染毒素，以250 ppb。对照α阳性？控制饮食，生长参数显着（p <0.05）在250ppb黄曲霉毒素喂养雏鸡中较低？实验和抗体滴度对Nd的显着（p <0.05）较低？阴性？控制饮食？从35到42天年龄。酵母葡糖胺？和膨润土钠，单独和组合到含有痤疮的饮食改善了黄曲霉毒素的不良反应，但是0.1％？酵母葡甘露胺？补充于随着黄曲霉毒素的污染饮食被证明得多有效地改善了AF对ND的性能和肱骨抗扰度的不利影响的改善：αkey，肉类，肉鸡，0.1％酵母葡糖胺，性能，新城疫。

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