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首页> 外文期刊>African Journal of Biotechnology >Comparative study of antimicrobial activities of Aloe vera extracts and antibiotics against isolates from skin infections
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Comparative study of antimicrobial activities of Aloe vera extracts and antibiotics against isolates from skin infections

机译：芦荟提取物和抗生素对皮肤感染分离物的抗菌活性的比较研究

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摘要

Plants are of relevance to dermatology for both their beneficial and adverse effects on skin and skin disorders. One of the medicinal plants,?Aloe vera?(Aloe barbadensis?Miller), is reputed to have medicinal properties. For centuries, it has been used for an array of ailments such as?mild fever, wounds and burns, gastrointestinal disorders, diabetes, sexual vitality and fertility problems to cancer, immune modulation, AIDS and various skin diseases.?In this study,?antibacterial activity of leaf and gel extracts of?A. vera?were tested against gram positive and gram negative skin infections isolates. For this purpose, one hundred and fifteen bacterial strains were isolated from skin wounds, burns and acne patients from various hospitals of Karachi, a cosmopolitan and heavily populated city of Pakistan, and the strains were identified by conventional methods. Among the total isolates, 90% of the organisms were gram positive while the remaining 10% were gram negative. The gel extracts of?A. vera?showed antibacterial activity against both gram positive and gram negative isolates while the leaf extracts showed no such activity. In parallel, five standard antibiotics were also tested against the isolated strains. The data showed promising results in case of?A. vera?compared to five broad-spectrum antibiotics. Additionally, the study also demonstrated that the skin infectious isolates were resistant against broad-spectrum antibiotics.
机译：植物与皮肤病学具有相关性，对皮肤和皮肤病的有益和不良影响。药用植物之一，？芦荟？（芦荟Barbadensis？Miller）被众所述，具有药物性质。几个世纪以来，它已被用于一系列疾病，如癌症，免疫调节，艾滋病和各种皮肤病的疾病，如患者，如？轻度发烧，伤口和烧伤，胃肠障碍，糖尿病，性活力和生育问题。本研究，？叶片和凝胶提取物的抗菌活性？a。 Vera？针对革兰氏阳性和革兰氏阴性皮肤感染分离株。为此目的，从皮肤伤口，烧伤和痤疮患者，来自卡拉奇，一个大都市和大量人口的巴基斯坦城市，菌株的患者分离了一百五十个细菌菌株，并通过常规方法鉴定了菌株。在总分离物中，90％的生物体是克阳性，而剩余的10％是克阴性。凝胶提取物的？a。 Vera？显示针对革兰氏阳性和革兰氏阴性分离物的抗菌活性，而叶子提取物没有出现这种活性。平行，还针对分离的菌株测试了五种标准抗生素。数据显示出有希望的结果？a。 Vera？与五种广谱抗生素相比。此外，该研究还证明皮肤传染性分离物对广谱抗生素具有抗性。

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