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首页> 外文期刊>Archivos de la Sociedad Espa?ola de Oftalmología (English Edition) >Sensibilidad y especificidad del reflejo rojo en recién nacidos en Costa Rica
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Sensibilidad y especificidad del reflejo rojo en recién nacidos en Costa Rica

机译：哥斯达黎加新生儿红逆反射的敏感性和特异性

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Objective To compare the results of indirect ophthalmoscopy versus determination of the red reflex in newborns admitted to the intermediate neonatal intensive care unit. Methods All the patients (71) admitted to the intermediate neonatal intensive care unit from July to September of 2017 were screened with the red reflex. Immediately afterwards, they were pharmacologically dilated and indirect ophthalmoscopy was performed. All of the red-reflex screening and the funduscopic examination were performed by the same evaluator. Results A total of 14.1% (20/142) of the eyes had an altered red reflex. Indirect ophthalmoscopy revealed that 21.8% (31/142) of the eyes had intraocular abnormalities. Two of these eyes had optic nerve colobomas, two eyes had cataracts, and the rest had intra-retinal haemorrhages. Indirect ophthalmoscopy revealed that only 35% (7/20) of the eyes with an altered red reflex had intraocular disease. Indirect ophthalmoscopy also revealed that intraocular disease was present in 77.4% (24/31) of the eyes despite a normal red reflex. The false positive rate of the red reflex was calculated to be 9.2%, and the false negative rate was 16.9%. The sensitivity of the red reflex was only 56.4%, and the specificity was 89.5%. The positive predictive value was 70.4%, and the negative predictive value was 82.2%. Conclusions Neonatal screening with the red reflex is not sufficient to detect intraocular disease. A normal neonatal red reflex does no exclude intraocular disease. It has a specificity of nearly 90%, but its sensitivity is only 56%. Most retinal haemorrhages are undiagnosed as they cannot be detected with a red reflex.
机译：目的比较间接眼镜镜检查与新生儿录取中级新生儿重症监护单位的红色反射的结果。方法采用2017年7月至9月入院的所有患者（71）的所有患者（71）都以红色反射筛选。之后，它们立即进行药理学扩张，并进行间接眼镜检查。所有的红色反射筛查和眼底检查都由相同的评估员进行。结果总共14.1％（20/142）的眼睛有一个改变的红色反射。间接眼镜镜透露，21.8％（31/142）的眼睛具有眼内异常。这些眼睛中的两只眼睛有视神经colobomas，两只眼睛有白内障，其余的患有视网膜内出血。间接眼镜镜透露，只有35％（7/20）的红色反射的眼睛具有眼内疾病。间接眼镜镜又显示出在77.4％（24/31）的眼睛中，目光中的眼内疾病仍然存在正常的红色反射。红色反射的假阳性率计算为9.2％，假阴性率为16.9％。红色反射的敏感性仅为56.4％，特异性为89.5％。阳性预测值为70.4％，负预测值为82.2％。结论新生儿筛选红细胞不足以检测眼内疾病。正常的新生儿红色反射不排除眼内疾病。它的特异性近90％，但其敏感性仅为56％。大多数视网膜出血是未被用红色反射检测到的。

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