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首页> 外文期刊>Arquivos brasileiros de cardiologia. >Registro Multicêntrico de Takotsubo (REMUTA) – Aspectos Clínicos, Desfechos Intra-Hospitalares e Mortalidade a Longo Prazo
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Registro Multicêntrico de Takotsubo (REMUTA) – Aspectos Clínicos, Desfechos Intra-Hospitalares e Mortalidade a Longo Prazo

机译：Takotsubo（HEMBOR）的多中心记录 - 临床方面，医院内的结果和长期死亡率

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Background Takotsubo syndrome (TTS) is an acquired form of cardiomyopathy. National Brazilian data on this condition are scarce. The Takotsubo Multicenter Registry (REMUTA) is the first to include multicenter data on this condition in Brazil. Objective To describe the clinical characteristics, prognosis, in-hospital treatment, in-hospital mortality, and mortality during 1 year of follow-up. Methods This is an observational, retrospective registry study including patients admitted to the hospital with diagnosis of TTS and patients admitted for other reasons who developed this condition. Evaluated outcomes included triggering factor, analysis of exams, use of medications, complications, in-hospital mortality, and mortality during 1 year of follow-up. A significance level of 5% was adopted. Results The registry included 169 patients from 12 centers in the state of Rio de Janeiro, Brazil. Mean age was 70.9 ± 14.1 years, and 90.5% of patients were female; 63% of cases were primary TTS, and 37% were secondary. Troponin I was positive in 92.5% of patients, and median BNP was 395 (176.5; 1725). ST-segment elevation was present in 28% of patients. Median left ventricular ejection fraction was 40 (35; 48)%. We observed invasive mechanical ventilation in 25.7% of cases and shock in 17.4%. Mechanical circulatory support was used in 7.7%. In-hospital mortality was 10.6%, and mortality at 1 year of follow-up was 16.5%. Secondary TTS and cardiogenic shock were independent predictors of mortality. Conclusion The results of the REMUTA show that TTS is not a benign pathology, as was once thought, especially regarding the secondary TTS group, which has a high rate of complications and mortality.
机译：背景技术Takotubo综合征（TTS）是一种获得的心肌病。关于这种情况的国家巴西数据很少。 Takotsubo MultiCenter注册表（Remuta）是第一个包括在巴西在这种情况下包括多中心数据的内容。目的描述1年随访期间临床特征，预后，住院治疗，住院死亡率和死亡率。方法这是一个观察性的，回顾性的注册管理机构研究，包括患者诊断到医院的患者，诊断为TTS和患者承认制定这种情况的其他原因。评估结果包括引发因子，考试分析，使用药物，并发症，住院中的死亡率和1年后的死亡率。采用了5％的显着性水平。结果注册处包括169名来自巴西里约热内卢的12个中心的患者。平均年龄为70.9±14.1岁，90.5％的患者是女性; 63％的病例为初级TTS，37％是次要的。肌钙蛋白I在92.5％的患者中呈阳性，中位数BNP为395（176.5; 1725）。在28％的患者中存在ST段升高。中位左心室喷射级分是40（35; 48）％。我们观察到25.7％的病例和休克中的入侵机械通气17.4％。机械循环载体以7.7％使用。住院死亡率为10.6％，后续后的死亡率为16.5％。继发性TTS和心源性冲击是死亡率的独立预测因子。结论Remuta的结果表明，TTS不是良性病理学，曾经认为，特别是关于次级TTS组，其具有高度并发症和死亡率。

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