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首页> 外文期刊>Indian Journal of Ophthalmology >Spectrum of eye disorders in diabetes (SPEED) in India. Report # 2. Diabetic retinopathy and risk factors for sight threatening diabetic retinopathy in people with type 2 diabetes in India
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Spectrum of eye disorders in diabetes (SPEED) in India. Report # 2. Diabetic retinopathy and risk factors for sight threatening diabetic retinopathy in people with type 2 diabetes in India

机译：印度糖尿病（速度）的眼部疾病的光谱。报告＃2.印度2型糖尿病患者患有糖尿病性视网膜病的糖尿病视网膜病变和危险因素

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Purpose: To assess the proportion of people with type 2 diabetes mellitus (T2DM) with diabetic retinopathy (DR) and sight-threatening DR (STDR) and associated risk factors in select eye-care facilities across India. Methods: In this observational study, data of people with T2DM presenting for the first time at the retina clinic of eye-care facilities across India was recorded. Data collected in 2016 over 6 months included information on systemic, clinical, and ocular parameters. International Clinical Diabetic Retinopathy (ICDR) classification scale was used to grade DR. STDR was defined as presence of severe nonproliferative (NPDR), proliferative diabetic retinopathy (PDR), and/or diabetic macular edema (DME). Results: The analysis included 11,182 people with T2DM from 14 eye-care facilities (mean age 58.2 ± 10.6 years; mean duration of diabetes 9.1 ± 7.6 years; 59.2% male). The age-standardized proportion of DR was 32.3% (95%Confidence Interval, CI: 31.4-33.2) and STDR was 19.1% (95%CI: 18.4-19.8). DME was diagnosed in 9.1% (95%CI: 8.5-9.6) and 10.7% (95%CI: 10.1-11.3) people had PDR. Statistically significant factors associated with increased risk of DR (by multivariate logistic regression analysis) were: male gender (Odds ratio[OR] 1.57, 95%CI: 1.16-2.15); poor glycemic control–glycated hemoglobin (HbA1c 10%)(OR 2.39, 95% CI: 1.1-5.22); requirement of insulin (OR 2.55, 95%CI: 1.8-3.6);history of hypertension (OR 1.42, 95%CI: 1.06-1.88) and duration of diabetes 15 years (OR 5.25, 95%CI: 3.01-9.15). Conclusion: Diabetic retinopathy was prevalent in 1/3suprd/sup and sight-threatening DR in 1/5supth/sup of people with T2DM presenting at eye-care facilities in this pan-India facility-based study. The duration of diabetes was the strongest predictor for retinopathy.
机译：目的：评估2型糖尿病（T2DM）与糖尿病视网膜病变（DR）和威胁威胁危及印度选择眼部护理设施的危险因素的糖尿病（T2DM）的比例。方法：在这个观察到研究中，记录了T2DM的人士在印度跨境视线诊所第一次提出T2DM的数据。 2016年收集的数据超过6个月内包括有关全身，临床和眼部参数的信息。国际临床糖尿病视网膜病变（ICDR）分类规模用于级博士。 STDR被定义为存在严重的非增殖（NPDR），增殖性糖尿病视网膜病变（PDR）和/或糖尿病黄斑水肿（DME）。结果：分析包括11,182人，T2DM的14个护目理设施（平均年龄为58.2±10.6岁;糖尿病的平均持续时间9.1±7.6岁; 59.2％的男性）。 DR的年龄标准化比例为32.3％（95％置信区间，CI：31.4-33.2）和STDR为19.1％（95％CI：18.4-19.8）。 DME被诊断为9.1％（95％CI：8.5-9.6）和10.7％（95％CI：10.1-11.3）人员患有PDR。与博士（多元逻辑回归分析）增加的统计学意义有关：男性性别（差距[或] 1.57,95％CI：1.16-2.15）;血糖对照糖尿病糖尿病血糖血红蛋白（HBA1C> 10％）（或2.39,95％CI：1.1-5.22）;胰岛素的要求（或2.55,95％CI：1.8-3.6）;高血压病史（或1.42,95％CI：1.06-1.88）和糖尿病持续时间> 15岁（或5.25,95％CI：3.01-9.15） 。结论：糖尿病视网膜病患者在1/3 Rd 和威胁威胁的威胁下，在这个泛印度的眼睛护理设施中的1/5 Th 威胁危险的DR基于设施的研究。糖尿病的持续时间是视网膜病变的最强预测因子。

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