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Electrochemical Regeneration of the Cofactor NADH Employing a Carbon Nanofibers Cathode

机译:采用碳纳米纤维阴极的辅因子NADH的电化学再生

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A cathode made of carbon nanofibers (CNFs) grown on a stainless steel mesh was used for thereduction of an oxidized form of the enzymatic cofactor nicotinamide adenine dinucleotide (NAD+) toenzymatically-active 1,4-NADH, i.e. for the electrochemical regeneration of 1,4-NADH. The CNFcathode was shown to enable fast electrochemical NAD+ reduction kinetics and high NAD+ conversionrelative to the glassy carbon and stainless steel mesh cathodes alone. The CNF cathode was also foundto be highly selective, yielding a 99.3 0.6 % pure 1,4-NADH product. As such, the CNF cathode is agood candidate for the electrochemical regeneration of 1,4-NADH in biochemical reactors andbiosensors.
机译:在不锈钢网上生长的碳纳米纤维(CNF)制成的阴极用于氧化形式的酶辅因子烟酰胺腺嘌呤二核苷酸(NAD +)才能中的活性1,4-NADH,即为1,即电化学再生, 4-nadh。显示CNFCATHODE以单独为玻璃碳和不锈钢网状阴极提供快速电化学NAD +降低动力学和高NAD +转换+。还发现CNF阴极是高度选择性的,得到99.3 0.6%纯1,4-纳米产物。因此,CNF阴极是生物化学反应器中1,4-NADH电化学再生的Agood候选者。

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