...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Environmental Research and Public Health >Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage
【24h】

Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage

机译：在运动诱导的肌肉损伤后，Myostatin A55T基因型与强度恢复有关

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Myostatin A55T genotype is one of the candidates showing inter-individual variation in skeletal muscle phenotypes. The aim of this study was to investigate the effect of the myostatin A55T genotype on markers of muscle damage after eccentric exercise. Forty-eight young, healthy male college students (age = 24.8 ± 2.2 years, height = 176.7 ± 5.3 cm, weight = 73.7 ± 8.3 kg) were enrolled in this study, and muscle damage was induced through 50 reps of maximal eccentric muscle contraction. As markers of muscle damage, maximal isometric strength (MIS), muscle soreness, creatine kinase (CK), and aspartate transaminase (AST) were measured. Myostatin A55T genotypes were classified into homozygous myostatin A55T allele (AA, n = 34, 72%), heterozygous myostatin A55T allele (AT, n = 13, 26%), and homozygous mutant carriers (TT, n = 1, 2%). After eccentric exercise, the subjects with heterozygous for AT showed markedly quicker MIS recovery compared to the AA group ( p = 0.042). However, there were no significant variations in muscle soreness ( p = 0.379), CK ( p = 0.955), and AST ( p = 0.706) among the groups. These results suggest that AT in myostatin A55T genotype may be associated with quicker strength recovery following exercise-induced muscle damage.
机译：Myostatin A55T基因型是显示骨骼肌表型细胞间变异的候选者之一。本研究的目的是探讨肌抑素A55T基因型对偏心运动后肌肉损伤标志物的影响。四十八名年轻，健康男大学生（年龄= 24.8±2.2岁，高度= 176.7±5.3厘米，重量= 73.7±8.3千克）注册了这项研究，肌肉损伤诱导通过50次最大偏心肌收缩诱导。作为肌肉损伤的标记，测量最大等距强度（MIS），肌肉酸痛，肌酸激酶（CK）和天冬氨酸转氨酶（AST）。将Myostatin A55T基因型分为纯合肌肉素A55T等位基因（AA，N = 34,72％），杂合肌肉素A55T等位基因（AT，N = 13,26％）和纯合突变载体（TT，N = 1,2％） 。偏心运动后，与AA基团相比，杂合的受试者在杂合出现明显更快的MIS恢复（P = 0.042）。然而，肌肉疼痛（p = 0.379），CK（P = 0.955），AST（P = 0.706）中没有显着变化。这些结果表明，在运动诱导的肌肉损伤后，在Myostatin A55T基因型中可能与更快的强度恢复相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号