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首页> 外文期刊>International Journal of Chronic Diseases >Usefulness of qSOFA and ECOG Scores for Predicting Hospital Mortality in Postsurgical Cancer Patients without Infection
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Usefulness of qSOFA and ECOG Scores for Predicting Hospital Mortality in Postsurgical Cancer Patients without Infection

机译：QSOFA和ECOG分数预测后期癌症患者医院死亡率的有用性，没有感染

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Background. The quick sequential organ failure assessment (qSOFA) and the Eastern Cooperative Oncologic Group (ECOG) scale are simple and easy parameters to measure because they do not require laboratory tests. The objective of this study was to compare the discriminatory capacity of the qSOFA and ECOG to predict hospital mortality in postsurgical cancer patients without infection. Methods. During the period 2013–2017, we prospectively collected data of all patients without infection who were admitted to the ICU during the postoperative period, except those who stayed in the ICU for 24 hours or patients under 18 years. The ECOG score during the last month before hospitalization and the qSOFA performed during the first hour after admission to the intensive care unit (ICU) were collected. The primary outcome for this study was the in-hospital mortality rate. Results. A total of 315 patients were included. The ICU and hospital mortality rates were 6% and 9.2%, respectively. No difference was observed between the qSOFA [AUC=0.75 (95% CI = 0.69-0.79)] and the ECOG scores [AUC=0.68 (95%CI =0.62-0.73)] (p=0.221) for predicting in-hospital mortality. qSOFA greater than 1 predicted in-hospital mortality with a high sensitivity (100%) but low specificity (38.8%); positive predictive value of 26.3% and negative predictive value of 93.1% compared to 74.4% of specificity, 55.1% of sensitivity%; positive predictive value of 18% and negative predictive value of 94.2% for an ECOG score greater than 1. Multivariable Cox regression analysis identified two independent predicting factors of in-hospital mortality, which included ECOG score during the last month before hospitalization (HR: 1.46; 95 % CI: 1.06-2.00); qSOFA calculated in the first hours after ICU admission (OR: 3.17; 95 % CI: 1.79–5.63). Conclusion. No difference was observed between the qSOFA and ECOG for predicting in-hospital mortality. The qSOFA score performed during the first hour after admission to the ICU and ECOG scale during the last month before hospitalization were associated with in-hospital mortality in postsurgical cancer patients without infection. The qSOFA and ECOG score have a potential to be included as early warning tools for hospitalized postsurgical cancer patients without infection.
机译：背景。快速顺序器官失败评估（QSOFA）和东方合作型肿瘤组（ECOG）规模是简单且简单的参数，因为它们不需要实验室测试。本研究的目的是比较QSOFA和ECOG的歧视能力，以预测未感染的后期癌症患者的医院死亡率。方法。在2013-2017期间，我们在术后期间预先收集到ICU的无感染的所有患者的数据潜在，除了在ICU持续24小时或18岁以下的患者。收集了在住院前的上个月内的ECOG分数，并收取了在入院后的第一个小时内进行的QSOFA进行收集到重症监护股（ICU）。本研究的主要结果是院内死亡率。结果。共有315名患者。 ICU和医院死亡率分别为6％和9.2％。在QSOFA [AUC = 0.75（95％CI = 0.69-0.79）之间没有观察到差异，并且ECOG谱分数[AUC = 0.68（95％CI = 0.62-0.73）]（p = 0.221），用于预测住院内部死亡率。 QSOFA大于1预测住院内死亡率，具有高灵敏度（100％）但特异性低（38.8％）;阳性预测值为26.3％，阴性预测值为93.1％，比特异性的74.4％，55.1％的灵敏度％; ECOG评分的阳性预测值为18％和负预测值为94.2％的ECOG评分大于1.多变量的COX回归分析确定了两种自主预测因素的住院死亡率，其中包括在住院前的上个月内的ECOG评分（HR：1.46 ; 95％CI：1.06-2.00）; QSOFA在ICU入院后的第一小时计算（或：3.17; 95％CI：1.79-5.63）。结论。在QSOFA和ECOG之间没有观察到预测住院医生死亡率的差异。在入院前的上个月入院前的ICU和Ecog规模的第一个小时内进行的QSOFA得分在没有感染的后期癌症患者中与住院治疗相关的医院死亡率。 QSOFA和ECOG评分有可能被包括在没有感染的情况下为住院后的后勤癌症患者的预警工具。

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