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首页> 外文期刊>International Journal of Research in Medical Sciences >Alveolar rhabdomyosarcoma in children with histomorphological review
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Alveolar rhabdomyosarcoma in children with histomorphological review

机译：肺泡横纹肌肉瘤在儿童患有组织形态审查

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Rhabdomyosarcomas (RMS) are aggressive malignant neoplasm of mesenchymal origin, related to skeletal muscle lineage. These are the most common soft tissue tumors in children. The diagnosis is made by microscopic analysis and ancillary techniques like immunohistochemistry, electron microscopy, cytogenetics and molecular biology. We encountered a case of a 03 years old child who presented with a tender, reddish, soft swelling over cheek for three weeks. The FNAC was reported as a small round cell tumor, Probably Primitive Neuroectodermal Tumor (PNET). The biopsy of tumor revealed a small round cell tumor with an alveolar pattern. Tumor giant cells were absent and mitotic figures were infrequent. Hence, differentials of alveolar rhabdomyosarcoma and PNET were rendered. Immunohistochemistry (IHC) demonstrated desmin positivity. Thus, a final diagnosis of alveolar rhabdomyosarcoma was offered.
机译：横纹肌肉瘤（rms）是间充质瘤的侵袭性恶性肿瘤，与骨骼肌谱系有关。这些是儿童中最常见的软组织肿瘤。诊断是通过显微镜分析和辅助技术进行的免疫组织化学，电子显微镜，细胞遗传学和分子生物学制成。我们遇到了一个03岁的孩子，他们在脸颊上呈现出温柔，红色，软肿胀，持续三周。将FNAc报告为小圆形细胞肿瘤，可能是原始神经分区肿瘤（PNET）。肿瘤的活检显示了具有肺泡图案的小圆形细胞肿瘤。肿瘤巨细胞不存在，有丝分裂的数字不常见。因此，提供了肺泡横纹肌肉瘤和PNET的差异。免疫组织化学（IHC）展示了亡灵积极性。因此，提供了肺泡横纹肌肉瘤的最终诊断。

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