...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Reproduction, Contraception, Obstetrics and Gynecology >A prospective clinical trial to evaluate the role of very low dose mifepristone 10 mg in medical management of uterine leiomyoma in tertiary care hospital from North West India
【24h】

A prospective clinical trial to evaluate the role of very low dose mifepristone 10 mg in medical management of uterine leiomyoma in tertiary care hospital from North West India

机译：一种临床临床试验，以评估非常低剂量米非司酮10毫克在印度西北三级护理医院子宫平瘤医学管理中的作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Uterine leiomyomas are the most common benign tumours of the uterus and also the most common benign solid tumor in female. It arises from the uterine smooth muscles (myometrium) but contain varying amount of fibrous connective tissue. Aim of study was to evaluate the efficacy of very low dose Mifepristone (10 mg) on leiomyoma volume and its related symptoms. Methods: This was a prospective clinical study. 30 women met with the inclusion criteria and giving informed consent for the study. Results: Mean myoma volume was 60.32±51.89 at initial visit and 36.13±48.54 at 3 months follow up visit with 40.1% reduction which was statistically significant difference (p 0.001). Mean PBAC score in Group I was 155.53±21.70 at initial visit and 0.97±2.97 at 3 months follow up visit with 99.3% reduction which was statistically significant (p 0.001). Conclusions: Mifepristone 10 mg is efficacious in term of control of bleeding, alleviation of pain related symptoms with few side effects. So low dose mifepristone can be used as a suitable option for women with symptomatic fibroids in perimenopausal periods or patients not willing or fit for surgery.
机译：背景：子宫平滑肌瘤是子宫最常见的良性肿瘤，也是女性中最常见的良性实体瘤。它由子宫平滑肌（Myometrium）产生，但含有不同量的纤维结缔组织。研究的目的是评估非常低剂量米非司酮（10 mg）对平滑肌瘤的疗效及其相关症状的疗效。方法：这是一项前瞻性临床研究。 30名妇女讨论了纳入标准，并为该研究提供了知情同意。结果：初步访问中的平均肌瘤体积为60.32±51.89，3个月36.13±48.54跟进，随访40.1％，差异有统计学意义（P <0.001）。在初步访问中，我的平均PBAC评分为155.53±21.70，在3个月内进行了0.97±2.97，随访99.3％，统计学意义（P <0.001）。结论：米非司酮10毫克在出血控制期间是有效的，患有少量副作用的疼痛相关症状。因此，低剂量米糊代酮可以用作患有症状期或不愿意或适合手术的患者患有症状肌瘤的妇女的合适选择。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号