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首页> 外文期刊>International Journal of Nanomedicine >Recent Developments in the Facile Bio-Synthesis of Gold Nanoparticles (AuNPs) and Their Biomedical Applications
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Recent Developments in the Facile Bio-Synthesis of Gold Nanoparticles (AuNPs) and Their Biomedical Applications

机译：近期生物合成金纳米颗粒（AUNP）及其生物医学应用的发展

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Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to have profound applications in medicine. There are various methods to synthesize AuNPs which are generally categorized into two main types: chemical and physical synthesis. Continuous efforts have been devoted to search for other more environmental-friendly and economical large-scale methods, such as environmentally friendly biological methods known as green synthesis. Green synthesis is especially important to minimize the harmful chemical and toxic by-products during the conventional synthesis of AuNPs. Green materials such as plants, fungi, microorganisms, enzymes and biopolymers are currently used to synthesize various NPs. Biosynthesized AuNPs are generally safer for use in biomedical applications since they come from natural materials themselves. Multiple surface functionalities of AuNPs allow them to be more robust and flexible when combined with different biological assemblies or modifications for enhanced applications. This review focuses on recent developments of green synthesized AuNPs and discusses their numerous biomedical applications. Sources of green materials with successful examples and other key parameters that determine the functionalities of AuNPs are also discussed in this review.
机译：广泛研究纳米颗粒（AUNP）纳米颗粒（NPS），已知在医学中具有深远的应用。有各种方法来合成AUNP，通常分为两种主要类型：化学和物理合成。不断努力寻找其他更环保和经济的大规模方法，例如被称为绿色合成的环保生物方法。绿色合成尤为重要，可在常规合成AUNPS期间最小化有害化学和毒性副产物。植物，真菌，微生物，酶和生物聚合物等绿色材料目前用于合成各种NPS。生物合成的aUnps通常更安全，以便在生物医学应用中使用，因为它们本身来自天然材料。当与不同的生物组件或增强应用的修改结合使用时，AUNP的多个表面功能允许它们更加坚固且更灵活。本综述重点介绍了绿色合成的AUNP的最新发展，并讨论了其众多生物医学应用。在本次审查中还讨论了具有成功示例和其他重点参数的绿色材料来源以及确定AUNP的功能的关键参数。

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