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首页> 外文期刊>International Journal of Surgical Oncology >Thyroidectomy as Treatment of Choice for Differentiated Thyroid Cancer
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Thyroidectomy as Treatment of Choice for Differentiated Thyroid Cancer

机译：甲状腺切除术作为分化甲状腺癌选择的选择

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Background. Despite a large amount of data, the optimal surgical management of differentiated thyroid cancer remains controversial. Current guidelines recommend total thyroidectomy if primary thyroid cancer is 4?cm, while for tumors that are between 1 and 4?cm in size, either a bilateral or a unilateral thyroidectomy may be appropriate as surgical treatment. In general, total thyroidectomy would seem to be preferable because subtotal resection can be correlated with a higher risk of local recurrences and cervical lymph node metastases; on the other hand, total thyroidectomy is associated with more complications. Methods. This is a retrospective study conducted on 359 patients with differentiated thyroid cancer, subjected to total thyroidectomy. Our aim was to correlate clinical and pathological features (extrathyroid tumor growth, bilaterality, nodal and distant metastasis) with patient (gender and age) and tumor (size and histotype) characteristics. Moreover, we recorded postoperative complications, including hypoparathyroidism and laryngeal nerve damage. Results. In our study, we found a high occurrence of pathological features indicating cancer aggressiveness (bilaterality, nodal metastases, and extrathyroid invasion). On the other hand, total thyroidectomy was associated with relatively low postsurgical complication rates. Conclusions. Our data support the view that total thyroidectomy remains the first choice for the routine treatment of differentiated thyroid cancer.
机译：背景。尽管数据大量数据，但分化的甲状腺癌的最佳手术管理仍然存在争议。目前的指导方针建议总甲状腺切除术，如果原发性甲状腺癌>4Ωcm，而对于尺寸为1-4Ω·cm的肿瘤，双侧或单侧甲状腺切除术可能适合作为手术治疗。通常，总甲状腺切除术似乎是优选的，因为小梗切除术可以与局部复发和宫颈淋巴结转移的风险较高;另一方面，总甲状腺切除术与更多并发症有关。方法。这是对359例分化的甲状腺癌患者进行的回顾性研究，经过全甲状腺切除术。我们的目的是将患者（性别和年龄）和肿瘤（大小和组织型）特征相关的临床和病理特征（含脱脂瘤肿瘤生长，双侧，节点和远离转移）。此外，我们记录了术后并发症，包括过胆管性和喉神经损伤。结果。在我们的研究中，我们发现了表明癌症侵袭性（双侧，节点转移和脱酸盐侵袭）的高病理特征。另一方面，总甲状腺切除术与相对低的后尿剂并发症率有关。结论。我们的数据支持该视图，甲状腺切除术仍然是常规治疗分化甲状腺癌的首选。

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