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首页> 外文期刊>Italian Journal of Medicine >Comparison of different prognostic scores for risk stratification in septic patients arriving to the Emergency Department
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Comparison of different prognostic scores for risk stratification in septic patients arriving to the Emergency Department

机译：脓毒症患者风险分层不同预后评分的比较

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We evaluated the prognostic performance of systemic inflammatory response syndrome (SIRS), sequential organ failure assessment (SOFA), quick-SOFA (qSOFA), modified early warning score (MEWS), lactates and procalcitonin in septic patients. Prospective study on adults with sepsis in the Emergency Department (ED). Area under the Receiver operator characteristic curve (AUC) was calculated to assess how scores predict mortality at 30 and 60 days (d) and upon admission to Intensive care unit (ICU). Among 469 patients, mortality was associated with higher SOFA, qSOFA, MEWS and lactates level. ICU admission was associated with higher SOFA, procalcitonin and MEWS. Prognostic performance for mortality were: SOFA AUC 30 d 0.76 (0.69-0.81); 60 d 0.74 (0.68-0.79); qSOFA AUC 30 d 0.72 (0.66-0.79); 60 d 0.73 (0.67-0.78) and lactates AUC 30 d 0.71 (0.60-0.82); 60d 0.65 (0.54- 0.73). For the outcome ICU admission, procalcitonin had the highest AUC [0.66 (0.56-0.64], followed by SOFA [0.61 (0.54-0.69)] and MEWS [0.60 (0.53-0.67)]. SOFA, qSOFA and lactates assessment after arrival in the ED have a good performance in detecting patients at risk of mortality for sepsis. Procalcitonin is useful to select patients that will need ICU admission.
机译：我们评估了系统性炎症反应综合征（SIRS），顺序器官衰竭评估（沙发），快速沙发（QSOFA），修饰早期预警得分（MEWS），乳酸和生效性患者的预后性能。急诊部（ED）中脓毒症成年人的前瞻性研究。计算接收机操作员特征曲线（AUC）下的区域，以评估分数在30日和60天（d）及入院后如何预测死亡率（ICU）。在469名患者中，死亡率与高等沙发，QSOFA，MEWS和乳酸水平有关。 ICU入院与高等沙发，ProCalcitonin和Mews相关联。预后的死亡性能是：沙发AUC 30 D 0.76（0.69-0.81）; 60 d 0.74（0.68-0.79）; QSOFA AUC 30 D 0.72（0.66-0.79）; 60 d 0.73（0.67-0.78）和乳酸AUC 30d 0.71（0.60-0.82）; 60d 0.65（0.54- 0.73）。对于ICU入院的结果，ProCalcitonin具有最高的AUC [0.66（0.56-0.64]，其次是沙发[0.61（0.54-0.69）]和MEWS [0.60（0.53-0.67）]。抵达后沙发，QSOFA和乳酸乳酸乳酸盐评估ED在检测败血症的死亡风险的患者中具有良好的性能。ProCalcitonin可用于选择需要ICU入学的患者。

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