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A case of chronic thromboembolic pulmonary hypertension

机译:慢性血栓栓塞肺动脉高压病例

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Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially fatal complication of pulmonary embolism (PE). Organized thrombus in the pulmonary artery causes a chronic obstruction, leading to a vascular system remodeling, an increase of pulmonary vascular resistance and a chronic pulmonary hypertension. Epidemiology is mostly unknown due to the difficult diagnostic process that often leads to a late diagnosis: findings of persistent pulmonary hypertension (PH), despite correct treatment of PE, lead to the diagnostic suspect. The first choice treatment is pulmonary endarterectomy (PEA) associated with lifelong anticoagulant therapy with vitamin K antagonist. We present the case of a 53-year-old male affected by dyspnea for months, admitted to a sub-intensive care unit for intermediate low-risk PE; echocardiography showed signs of PH persisting after anticoagulant therapy; after 2 months of specific treatment the diagnosis of CTEPH was confirmed and the patient was successfully treated with PEA.
机译:慢性血栓栓塞肺动脉高压(CTEPH)是肺栓塞(PE)的潜在致命并发症。有组织的血栓在肺动脉中引起慢性梗阻,导致血管系统重塑,肺血管抗性的增加和慢性肺动脉高压。流行病学大多是未知的诊断过程往往导致晚期诊断:持续肺动脉高血压(pH)的发现,尽管对PE正确治疗,导致诊断嫌疑人。第一选择治疗是与维生素K拮抗剂终身抗凝血治疗相关的肺下气肌切除术(豌豆)。我们展示了一个53岁男性受到呼吸困难影响的患者,达到了一个用于中间低风险PE的分解保健单位;超声心动图显示抗凝治疗后pH值持续存在的迹象;经过2个月的特定治疗后,证实了CTEPH的诊断,患者用豌豆成功处理。

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