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首页> 外文期刊>Endoscopy International Open >Diagnostic utility of linked color imaging in the evaluation of colonic mucosal inflammation in ulcerative colitis: a pilot study
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Diagnostic utility of linked color imaging in the evaluation of colonic mucosal inflammation in ulcerative colitis: a pilot study

机译：联系彩色成像在溃疡性结肠炎结肠粘膜炎症评价中的诊断效用：试验研究

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Background and aims?Recent studies recommend histological mucosal healing of intestinal tissue as a treatment goal in ulcerative colitis (UC). Linked-color imaging (LCI) is a new endoscopy system that enhances the color differences of the gastrointestinal mucosa. We investigated the efficacy of LCI in the evaluation of intestinal activity, including the histological activity in UC. Method?A total of 21 UC patients who were evaluated by the LASEREO system (FUJIFILM Co., Tokyo, Japan) were enrolled from August to December in 2016. All of the target points were observed by conventional white-light imaging (WLI) and LCI and biopsied from the region of interest in each view. We quantified the color tones of 73 biopsied points on WLI and LCI using the L*a*b* color value (WLI-L, WLI-a, WLI-b, and LCI-L, LCI-a, LCI-b). We then investigated the relationships among the L*a*b* color values, endoscopic findings, and histological healing. Results?The average LCI-a and LCI-b values of patients with high mucosal activity disease were significantly higher than in those with mucosal healing (P??0.01), and only LCI-a was significantly correlated with the score for histological healing. With regard to the other color values (LCI-L and all WLI values), there were no statistically significant differences in terms of average color value and correlation between patients with high mucosal activity and those with mucosal healing. In addition, the difference in the average color values with LCI and WLI was 7.1 and 3.1, respectively. Conclusion?LCI is more useful than WLI for the visualization and evaluation of mucosal inflammation in UC.
机译：背景和目标？最近的研究推荐肠组织的组织学粘膜愈合作为溃疡性结肠炎（UC）的治疗目标。链接 - 彩色成像（LCI）是一种新的内窥镜检查系统，可增强胃肠粘膜的颜色差异。我们研究了LCI在肠道活性评估中的疗效，包括UC中的组织学活动。方法？总共21例由Laseero System（Fujifilm Co.，Tokyo，Japan）评估的21例UC患者于2016年8月至12月份注册。通过常规白光成像（WLI）和常规观察所有目标点LCI和每个观点的兴趣区域的活检。我们使用L * A * B *颜色值（WLI-L，WLI-A，WLI-B和LCI-A，LCI-1，LCI-A，LCI-B）量化了73个活检点的色调和LCI的色调。然后，我们研究了L * A * B *颜色值，内窥镜发现和组织学愈合之间的关系。结果？高粘膜活性疾病患者的平均LCI-A和LCI-B值明显高于粘膜愈合（P？<β01），并且只有LCI-A与组织学愈合的分数显着相关。关于其他颜色值（LCI-L和所有WLI值），在高粘膜活动患者和粘膜愈合的患者之间的平均颜色值和相关性方面没有统计学上显着差异。此外，LCI和WLI的平均颜色值的差异分别为7.1和3.1。结论αslci比WLI更有用，用于UC中粘膜炎症的可视化和评估。

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