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Case of early-stage gastric cancer identified in the gastric mucosa with lanthanum phosphate deposition

机译：含有镧粘液沉积的胃粘膜中鉴定早期胃癌的情况

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Background and study aims?A 78-year-old man with Helicobacter pylori infection had been undergoing hemodialysis for chronic renal failure and receiving lanthanum carbonate preparations for 3 years. Endoscopy revealed fine white granular discoloration throughout the stomach, a moderately reddish depression on the lesser curvature of the gastric angle, and white granular discoloration in the surrounding area. A magnified image using narrow-band imaging showed that the depressed part had irregular vascular and pit structures. We established a diagnosis of intramucosal gastric cancer and performed endoscopic submucosal dissection. Histopathological examination revealed a well-differentiated adenocarcinoma that was confined to the mucosa of the depressed area. Moreover, using an electron probe microanalyzer-equipped electron microscope, we found that the degree of lanthanum deposition was lower in the tumor region than in the non-tumor region. Thus, the current case can help in understanding the relationship between lanthanum deposition and early-stage gastric cancer. Because gastric cancers can occur in lanthanum deposit-containing mucosa, esophagogastroduodenoscopy should be used carefully after understanding the characteristics of early- stage gastric cancer in such cases.
机译：背景和研究旨在？一名78岁的男子幽门螺杆菌感染的人已经进行了慢性肾功能衰竭的血液透析，并接受碳酸镧制剂3年。内窥镜检查显示出整个胃的细白粒状变色，对胃角较小的曲率较小的抑郁症，以及周围地区的白色颗粒变色。使用窄带成像的放大图像显示凹陷部分具有不规则的血管和凹坑结构。我们建立了对植物胃癌的诊断并进行了内窥镜粘膜粘膜释放。组织病理学检查显示出良好分化的腺癌，其被限制在抑郁区域的粘膜上。另外，使用电子探针微分析仪的电子显微镜，我们发现肿瘤区沉积程度低于非肿瘤区。因此，目前的情况可以有助于理解镧沉积和早期胃癌之间的关系。由于胃癌含有含镧沉积物的粘膜，因此在理解这种情况下了解早期胃癌的特征后应仔细使用食管藻毒型检查。

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