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The “Twist-Needle” – a new concept for endoscopic ultrasound-guided fine needle-biopsy

机译:“扭曲针” - 内窥镜超声引导细针活检的新概念

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Background and study aims?Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) represents a standard method for tissue acquisition of lesions adjacent to the gastrointestinal wall. Needles of 19 gauge acquire more tissue than needles with a smaller diameter, but are often unable to penetrate solid, rigid masses. In this study we evaluated a novel prototype that links forward movement of the needle to rotation of the needle tip. Materials and methods?Two needle-models that generate either a regular axial movement or a combination of axial movement with rotation of the needle tip were compared ex vivo for measurement of pressure needed to penetrate artificial tissue. Furthermore, a standard 19-gauge EUS-FNB needle was compared to a modified model (“Twist Needle”) in an ex vivo model to measure the amount of tissue obtained. Results?Pressure measurements using the rotating needle revealed that significantly less pressure is needed for penetration compared to the regular axial movement (mean ± SEM; 3.7?±?0.3 N vs. 5.5?±?0.3 N). Using the modified 19-gauge “Twist Needle” did not diminish tissue acquisition measured by surface amount compared to a standard needle (37?±?5 mm2 vs. 35?±?6 mm2). Conclusion?The method of rotation of an EUS-FNB needle tip upon forward movement requires less pressure for penetration but does not diminish tissue acquisition. Hence, the concept of our “Twist Needle” may potentially reduce some of the current limitations of standard EUS-FNB.
机译:背景和研究旨在?内窥镜超声引导的细针活检(EUS-FNB)代表了组织与胃肠壁相邻的病变的标准方法。 19规格的针头比具有较小直径的针头获得更多的组织,但通常无法穿透固体刚性质量。在该研究中,我们评估了一种新的原型,该原型链接针头向前移动到针尖的旋转。材料和方法?将常规轴向运动的两个针模型与针尖的旋转进行了常规轴向运动或轴向运动的组合,以用于测量穿透人工组织所需的压力。此外,将标准的19-Cauge EUS-FNB针进行比较,以在离体模型中进行改性模型(“扭曲针”)以测量所获得的组织量。结果?使用旋转针的压力测量显示,与常规轴向运动相比,渗透所需的压力显着较低(平均值±SEM; 3.7?±0.3n Vs. 5.5?±0.3 n)。使用改进的19-Cauge“扭转针”没有通过表面量测量的组织采集与标准针(37?±5mm 2与35.±6 mm2)相比测量。结论?向前移动时旋转EUS-FNB针尖的旋转方法需要较少的渗透压力,但不缩短组织采集。因此,我们的“扭转针”的概念可能会降低标准EUS-FNB的一些当前限制。

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