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首页> 外文期刊>Endoscopy International Open >Endoscopic closure of refractory esophageal fistula after esophagectomy using polyglycolic acid sheets: a pilot study
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Endoscopic closure of refractory esophageal fistula after esophagectomy using polyglycolic acid sheets: a pilot study

机译：使用聚乙醇酸片的食管切除术后难治性食管瘘的内窥镜闭合：试验研究

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Background and study aims?Esophageal fistulas after esophagectomy are associated with high mortality and poor quality of life. They are sometimes intractable to conservative management and surgery that increases mortality. Few studies have assessed use of polyglycolic acid (PGA) sheets with fibrin glue for esophageal fistulas. We investigated the safety of using PGA sheets with fibrin glue for esophageal fistulas after esophagectomy. Patients and methods?This was a single-center prospective pilot study. Patients who had refractory esophageal fistulas after esophagectomy were included. PGA sheets were filled in the fistula using biopsy forceps. Fibrin glue was applied to the PGA sheets. We repeated the procedure 1 week later. The outcome measures were the incidence of adverse events (AEs) and closure of the fistula. Results?Five patients were assessed. No adverse events were observed. The esophageal fistula was closed with the application of PGA sheets four times in 40?% (2/5) of the cases. Conclusions?PGA sheets with fibrin glue were safe for esophageal fistula closure after esophagectomy and do not involve the risk of AEs.
机译：背景和研究旨在？食管切除术后食管瘘与高死亡率和生活质量差有关。它们有时是棘手的管理和手术，增加死亡率。很少有研究评估了用纤维蛋白胶水用于食管瘘的纤维蛋白胶。我们调查了在食管切除术后使用纤维蛋白胶水使用PGA板材的安全性。患者和方法？这是一项单中心前瞻性试验研究。包括食管切除术后难治性食管瘘的患者。使用活组织检查钳将PGA片材填充在瘘管中。将纤维蛋白胶涂在PGA片材上。我们在1周后重复了手术。结果措施是不良事件（AES）和瘘管的发生率。结果？评估五名患者。没有观察到不良事件。用PGA片施用食管瘘40次（2/5）的案例封闭。结论？具有纤维蛋白胶水的PGA板材对于食管切除术后食管瘘闭合是安全​​的，并且不涉及AES的风险。

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