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First-in-man feasibility study of a novel ingestible magnetically inflated balloon capsule for treatment of obesity

机译:用于治疗肥胖的新型可磁气膨胀气囊胶囊的先进性可行性研究

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Intragastric balloons (IGBs) are an established treatment option for obesity. Major barriers to dissemination of IGBs include lack of long-term efficacy outcomes, safety concerns, cost, and tolerability. We developed a novel ingestible magnetically inflated balloon capsule (IMI-BC) in hopes of overcoming these challenges. The IMI-BC is significantly cheaper than IGBs currently available on the market. We performed proof-of-concept animal studies and a first-in-human feasibility study to demonstrate the feasibility of inflating the IMI-BC using an external magnet. Further studies are currently being conducted to evaluate the safety, tolerability, and long-term efficacy of the IMI-BC. When fully developed, we anticipate that this device will benefit obese patients.
机译:胃内气球(IGB)是肥胖的建立的治疗选择。传播IGB的主要障碍包括缺乏长期疗效结果,安全问题,成本和耐受性。我们开发了一种新颖的磁气充气气球胶囊(IMI-BC),希望克服这些挑战。 IMI-BC明显比市场上目前可用的IGB更便宜。我们进行了概念证明的动物研究和第一人工可行性研究,以证明使用外部磁铁膨胀IMI-BC的可行性。目前正在进行进一步的研究以评估IMI-BC的安全性,耐受性和长期疗效。在完全开发时,我们预计该设备将使肥胖患者受益。

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