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首页> 外文期刊>Endoscopy International Open >Improved detection of colorectal adenomas by high-quality colon cleansing
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Improved detection of colorectal adenomas by high-quality colon cleansing

机译：通过高质量的结肠清洁改善了结直肠腺瘤的检测

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Background and study aims?Reliable adenoma detection requires “adequate” bowel preparation. The adenoma detection rate (ADR) was assessed in patients with high-quality (stool-free) cleansing versus adequate cleansing. Patients and methods?This study was a post-hoc combined analysis of three randomized trials individually powered for cleansing quality assessment. Treatment-independent ADR was assessed versus colon cleansing quality by central readers using the Harefield Cleansing Scale (HCS) and the Boston Bowel Preparation Scale (BBPS). The number needed to treat (NNT) to find an additional patient with at least one adenoma was calculated for high-quality versus adequate-quality cleansing. Results?A total of 1749 patients were included. ADR increased with high-quality versus adequate-quality cleansing: HCS grade A versus B, 39?% (94/242) versus 27?% (336/1229); NNT?=?8.7; P??0.001.?ADR also increased with high-quality versus uniform adequate segmental cleansing scores: HCS grade A versus uniform segmental scores 2, 39?% (94/242) versus 26?% (97/379); NNT?=?7.5; P??0.001.?ADR increased with top-quality versus adequate segmental cleansing scores: HCS uniform segmental scores 4 versus 2, 54?% (21/39) versus 26?% (97/379); NNT?=?3.6; P??0.001.?ADR increased with BBPS 9 versus 6, 43?% (71/166) versus 26?% (247/950); NNT?=?6.0; P??0.001.?Right colon ADR increased with top-quality versus adequate cleansing: HCS 4 versus 2, 20?% (25/122) versus 11?% (121/1117); NNT?=?10.4; P??0.001 and BBPS 3 versus 2, 15?% (42/284) versus 11?% (130/1192); NNT?=?25.8; P?=?0.033. Conclusions?High-quality colon cleansing improves adenoma detection, and it should be a priority for bowel preparations for colonoscopy.
机译：背景和研究旨在？可靠的腺瘤检测需要“足够”的肠道准备。腺瘤检测率（ADR）在高质量（无尾部）清洁与充足的清洁患者中评估。患者和方法？该研究是一次性组合分析三项随机试验，单独用于清洁质量评估。使用Harefield清洁量表（HCS）和波士顿肠道制备量表（Bbps），通过中央读者评估与冒号清洁质量进行治疗。治疗（NNT）所需的数量用于寻找具有至少一种腺瘤的额外患者的高质量与适当质量的清洁。结果？共有1749名患者。 ADR高品质，相对于适量的清洁剂：HCS等级A对B，39？％（94/242）与27？％（336/1229）; nnt？=？8.7; p？<0.001.ODR也以高质量的与均匀性分段清洁分数增加：HCS等级A与均匀的节段性分数2,39？％（94/242）与26？％（97/379）; nnt？=？7.5; p？<0.001.ODR随着最高质量的增加而增加，而足够的节段清洁分数：HCS均匀的节段性分数4与2,54？％（21/39）与26？％（97/379）; nnt？=？3.6; p？<〜0.001.??与Bbps 9对6,43,43，43倍（71/166）与26？％（247/950）增加; nnt？=？6.0; p？<？0.001.?Right Colon ADR随着最高质量的增加而增加：HCS 4与2,20？％（25/122）与11？％（121/1117）; nnt？=？10.4; p？<〜0.001和Bbps 3对2,15？％（42/284）与11？％（130/1192）; nnt？=？25.8; p？= 0.033。结论？高质量的结肠清洁改善腺瘤检测，应该是集肠镜检查的肠道制剂的优先事项。

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