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首页> 外文期刊>Endoscopy International Open >Confocal endomicroscopy for evaluation of pancreatic cystic lesions: a systematic review and international Delphi consensus report
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Confocal endomicroscopy for evaluation of pancreatic cystic lesions: a systematic review and international Delphi consensus report

机译：共聚焦元素评估胰腺囊性病变：系统审查和国际德尔福共识报告

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Background and study aims?The aim of thi systematic review and consensus report is to standardize the practice of endoscopic ultrasound (EUS-guided needle-based confocal laser endomicroscopy (nCLE) for pancreatic cystic lesion (PCL) evaluation. Methods?We performed an international, systematic, evidence-based review of the applications, outcomes, procedural processes, indications, training, and credentialing of EUS-nCLE in management of PCLs. Based on available clinical evidence, preliminary nCLE consensus statements (nCLE-CS) were developed by an international panel of 15 experts in pancreatic diseases. These statements were then voted and edited by using a modified Delphi approach. An a priori threshold of 80?% agreement was used to establish consensus for each statement. Results?Sixteen nCLE-CS were discussed. Thirteen (81?%) nCLE-CS reached consensus addressing indications (non-communication PCL meeting criteria for EUS-FNA or with prior non-diagnostic EUS-FNA), diagnostic outcomes (improved accuracy for mucinous PCLs and serous cystadenomas with substantial interobserver agreement of image patterns), low incidence of adverse events (fluorescein-associated and pancreatitis), procedural processes (nCLE duration, manipulation of needle with probe), and training (physician knowledge and competence). Conclusion?Based on a high level of agreement pertaining to expert consensus statements, this report standardizes the practice of EUS-nCLE. EUS-nCLE should be systematically considered when EUS-FNA is indicated for PCL evaluation.
机译：背景和研究旨在的目标是系统审查和共识报告的目的是标准化内窥镜超声（EUS引导针对基于针的共聚焦激光端子复制（NCL）的胰腺囊性病变（PCL）评估的实践。方法？我们执行了一个国际在PCL的管理中，系统，证据基于循证的审查，审查eus-ncle的申请，结果，程序程序，指示，培训和全能的eus-ncle。根据可用的临床证据，由初步NCLS共识陈述（NCL-CS）开发国际胰遗传疾病的4个专家小组。然后使用改进的德尔福方法投票和编辑这些陈述。使用80？％协议的先验阈值来为每个陈述建立共识。结果？讨论了六十个ncle-cs。十三（81倍）NCLE-CS达到了共识解决适应症（EUS-FNA的非通信PCL会议标准或以前的非诊断EUS-FOS），诊断结果（用大量的Interobserver Appicate atfobserver达成的粘液pCLS和浆液性囊腺瘤的准确性），不良事件发生率低（荧光素相关和胰腺炎），程序过程（NCLE持续时间，针对探针操纵）和培训（医生知识和权限）。结论是基于与专家共识陈述有关的高水平协议，本报告标准化了EUS-NCLE的实践。当EUS-FNA指示用于PCL评估时，应系统地考虑EUS-NCLS。

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