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首页> 外文期刊>Endoscopy International Open >Is it time for Cold-Endoscopic Submucosal Dissection? A feasibility study in an esophageal and colorectal live porcine model
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Is it time for Cold-Endoscopic Submucosal Dissection? A feasibility study in an esophageal and colorectal live porcine model

机译：是否是冷 - 内窥镜粘膜粘膜清除术的时间？食管和结直肠生物猪模型的可行性研究

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Background and study aims?Use of cold endoscopic resection has increased due to excellent results with it and the ability to avoid electrosurgery related complications. The aim of this study was to evaluate the feasibility and safety of cold-endoscopic submucosal dissection (C-ESD) in an in vivo porcine model. Patients and methods?C-ESD with circumferential incision and submucosal dissection with a predominantly cold technique was tested in the esophagus and colorectum. Incision and dissection were attempted with a cold technique with a biopsy forceps and an endoscopic Maryland dissector. Large vessels were pre-coagulated with the latter device. Different traction methods were applied. Results?Twelve dissections were performed: four esophageal, four colonic, and four rectal. Tunnel and pocket methods were applied successfully. Full C-ESD was possible in the colorectum. In the esophagus, an initial incision had to be done with electrocautery. No major bleeding occurred. Two perforations occurred in the colon, one was endoscopically treated. Conclusions?Full C-ESD is feasible in the colorectum, whereas a small hot incision is needed in the esophagus. However, in 50?% of the colonic cases, there were perforations caused by the biopsy forceps making the circumferential incision. Therefore, potential benefits of endoscopic resection without cautery would warrant futures studies in humans initially in esophagus and rectal locations.
机译：背景和学习症状？使用冷的内窥镜切除因其具有优异的结果和避免电外科相关并发症的能力而增加。本研究的目的是评估冷 - 内窥镜粘膜粘膜清除（C-ESD）在体内猪模型中的可行性和安全性。患者和方法？在食道和结肠肠中测试了具有周向切口和具有主要冷技术的粘膜切口和粘膜释放的C-ESD。用活检钳和内窥镜马里兰州解剖员尝试切口和解剖。大容器用后一种装置预凝固。应用了不同的牵引方法。结果？进行12个剖析：四种食管，四种结肠和四个直肠。隧道和袖珍方法成功应用。在结肠肠中可以进行全C-ESD。在食道中，必须使用电烙术进行初始切口。没有发生重大出血。结肠中发生两个穿孔，一个是内窥镜治疗的。结论？完全C-ESD在结肠肠中是可行的，而食道需要小的热切口。然而，在50？％的结肠病例中，活检钳制造圆周切口引起的穿孔。因此，没有烧灼物的内镜切除潜在的益处将使最初在食道和直肠位置的人类中的期货研究。

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