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Characteristics of hypoglycaemic episodes in diabetic patients treated at the emergency room of a Portuguese tertiary centre, 2012‐2016

机译:糖尿病患者在葡萄牙大专院校急诊室患者低血糖发作特征,2012 - 2016年

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Objective To analyse changes in the characteristics of hypoglycaemic episodes treated in the emergency room of a tertiary hospital in Portugal between 2012 and 2016. Research Design and Methods We retrospectively analysed all emergency room reports for patients discharged with a diagnosis of hypoglycaemia between 2012 and 2016 and analysed demographic characteristics, type of diabetes and treatments, causes of hypoglycaemia and discharge destination. Patients without diabetes were excluded. Results In total, 676 hypoglycaemic episodes were analysed. Most patients were female (59%) and the median age of the patients was 71?years (interquartile range, 57‐81). The proportion of hypoglycaemic episodes relative to all emergency episodes decreased from 1.5% in 2012 to 1.0% in 2016 ( P ?.001). The proportion of patients with type 1 diabetes increased from 15.6% to 23.8%, while that of patients with type 2 diabetes decreased from 80.3% to 72.3% (nonsignificant differences). There was an increase in the use of insulin (67.1% to 85.4%, P =?.02) and a decrease in the use of insulin secretagogues (26.6% to 11.5%, P =?.03) over the study period. The rate of hospitalization dropped significantly from 11% in 2012 to 4.3% in 2015 and 5.4% in 2016 ( P =?.02). Conclusions Despite the increasing use of newer diabetes medications associated with a lower risk of hypoglycaemia, these episodes still require emergency care. The proportion of patients receiving insulin increased over the years, probably due to the slight increase in the prevalence of type 1 diabetes and the increasing replacement of secretagogues with insulin in type 2 diabetes.
机译:目的分析2012和2016年葡萄牙急诊室急诊室急诊室特征的变化。研究设计与方法我们回顾性分析了在2012年和2016年间诊断下出院的患者的急诊室报告分析了人口统计学特征,糖尿病和治疗类型,低血糖和排放目的地的原因。没有糖尿病的患者被排除在外。结果总计,分析了676个低血糖发作。大多数患者是女性(59%),患者的中位年龄为71岁?年(四分位数范围,57-81)。相对于所有急诊发作的低血糖发作的比例从2012年的1.5%降低至2016年的1.0%(P <001)。 1型糖尿病患者的比例从15.6%增加到23.8%,而2型糖尿病患者的患者从80.3%降至72.3%(不显着差异)。使用胰岛素的使用(67.1%至85.4%,P = 02),在研究期间使用胰岛素促分泌抑制剂的使用减少(26.6%至11.5%,p = 03)。 2012年的住院时间从2012年的11%下降到2015年的4.3%,2016年的5.4%(P = 02)。结论尽管利用较新的糖尿病药物的使用较低,但低血糖风险较低,这些事件仍需要紧急护理。多年来接受胰岛素的患者比例增加,可能是由于1型糖尿病患病率的略有增加以及患有2型糖尿病患者的胰岛素的替代术。

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