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首页> 外文期刊>Endocrine journal >Clinical Features and Prognostic Factors for Survival in Patients with Poorly Differentiated Thyroid Carcinoma and Comparison to the Patients with the Aggressive Variants of Papillary Thyroid Carcinoma
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Clinical Features and Prognostic Factors for Survival in Patients with Poorly Differentiated Thyroid Carcinoma and Comparison to the Patients with the Aggressive Variants of Papillary Thyroid Carcinoma

机译：甲状腺癌不良患者生存的临床特征和预后因素，与乳头状甲状腺癌侵袭性变异患者的患者

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References(28) Cited-By(37) We performed this study to compare the clinicopathologic features and outcomes between the patients with poorly differentiated thyroid carcinoma (PDTC) and the patients with the aggressive variants of papillary thyroid carcinoma (PTC). To evaluate the prognostic factors for survival of the patients with PDTC, we selected 49 patients with PDTC and 23 patients with the aggressive variants of PTC from three hospitals during the recent 15 years. The five-year survival rate and clinicopathologic features of the patients with PDTC were not different from those of the patients with the aggressive variants of PTC. Univariate analysis revealed the significant poor prognostic factors for survival of the patients with PDTC and the aggressive variants of PTC as follows: 1) an age more than 45 years, 2) a tumor size larger than 4 cm, 3) the presence of tumor invasion to extrathyroidal tissue or the trachea, 4) the presence of cervical lymph node invasion, 5) the presence of distant metastasis, 6) the absence of high-dose radioactive iodine (RAI) therapy, and 7) TNM stage II, III and IV. Distant metastasis and high-dose RAI therapy were independent significant predictors for survival of the patients with PDTC and the aggressive variants of PTC on multivariate analysis. However, distant metastasis was the only independent significant predictors for survival of the patients with PDTC excluding patients with the aggressive variants of PTC.
机译：参考文献（28）引用（37）我们进行了本研究，比较患有甲状腺癌（PDTC）和乳头状甲状腺癌（PTC）侵袭性变异患者患者之间的临床病理特征和结果。为了评估PDTC患者存活的预后因素，我们选择了49例PDTC和23名患者在近15年内从三家医院获得PTC的侵略性变种。 PDTC患者的五年存活率和临床病理特征与PTC侵袭性变异的患者的患者不同。单变量分析显示，PDTC患者生存和PTC的侵袭性变异如下：1）年龄超过45岁，2）肿瘤大于4厘米，3）存在肿瘤侵袭的肿瘤侵袭脱滴虫组织或气管，4）颈淋巴结侵袭，5）遥远的转移存在，6）没有高剂量放射性碘（RAI）治疗，7）TNM阶段II，III和IV 。远处转移和高剂量的RAI治疗是独立的重要预测因子，用于PDTC患者的存活以及PTC对多变量分析的侵袭性变异。然而，远处转移是PDTC患者的唯一独立的重要预测因子，不包括患者PTC的侵袭性变异。

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