• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European Heart Journal - Case Reports >Significant decrease in lipid core burden index following balloon dilation was associated with the leakage of cholesterol crystals in a patient: a case report
【24h】

Significant decrease in lipid core burden index following balloon dilation was associated with the leakage of cholesterol crystals in a patient: a case report

机译：球囊扩张后脂质核心负荷指数的显着降低与患者胆固醇晶体的泄漏有关：案例报告

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Near-infrared spectroscopy (NIRS) has been used for analysis the composition of the atherosclerotic plaque in coronary arteries. However, meaning of significant decrease in max lipid core burden index at 4?mm (max LCBIsub4mm/sub) during percutaneous coronary intervention (PCI) is poorly understood. Case summary A 64-year-old male with unstable angina underwent coronary angiography, which demonstrated a hazy tight culprit lesion in the mid-right coronary artery. Pre-intervention NIRS–intravascular ultrasound (NIRS–IVUS) and chemogram showed plaque with high lipid burden at the culprit lesion. Then, we used a distal protection device before PCI because of high max LCBIsub4mm/sub in the lesion. After pre-dilation with a scoring balloon, repeat NIRS–IVUS interrogation revealed an almost complete disappearance of the yellow signal and decrease in max LCBIsub4mm/sub (from 537 to 44) significantly, suggesting decrease in the lipid content of the plaque. Finally, a drug-eluting stent deployment followed by inflation of a non-compliant balloon led to an excellent result. After PCI, we detected trapped large amounts of debris on retrieval of the filter. Pathological diagnosis confirmed that trapped material was lipid-rich plaque including cholesterol crystals. Discussion This is the first report directly demonstrated that significant decrease in max LCBIsub4mm/sub at culprit lesion should be associated with the leakage of cholesterol crystals from lipid-rich plaque during PCI in the clinical patient.
机译：背景技术近红外光谱（NIRS）已被用于分析冠状动脉中动脉粥样硬化斑块的组成。然而，在经皮冠状动脉干预（PCI）期间4毫米（MAX LCBI 4mm ）的最大脂质核心负荷指数显着降低的意义差不多理解。案例概述了一个64岁的男性，不稳定的心绞痛接受了冠状动脉造影，这在中右冠状动脉中显示出朦胧的紧密罪魁祸首。介入前鼻腔血管内超声（NIRS-IVUS）和化学图显示出尖锐的病变高脂质负担的斑块。然后，我们在PCI之前使用了远端保护装置，因为Lesion中的高最大LCBI 4mm 。在用评分球囊预先扩展后，重复NIRS-IVUS询问显示黄色信号几乎完全消失，并显着降低了最大LCBI 4mm （从537〜44），表明脂质含量降低斑块。最后，一种药物洗脱支架部署，然后膨胀不合规的球囊导致出色的结果。在PCI之后，我们在检索过滤器中检测到大量的碎片。病理诊断证实，捕获的材料是富含脂质的斑块，包括胆固醇晶体。讨论这是第一个报告直接证明，罪魁祸首病变的最大LCBI 4mm 的显着降低应与在临床患者的PCI中富含富含脂质斑块的胆固醇晶体的泄漏相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号