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首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >Comparison of the Efficacy between Conventional Moxibustion and Smoke-Free Moxibustion on Knee Osteoarthritis: A Randomized Controlled Trial
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Comparison of the Efficacy between Conventional Moxibustion and Smoke-Free Moxibustion on Knee Osteoarthritis: A Randomized Controlled Trial

机译：膝关节骨关节炎常规艾灸与无烟灸之间的疗效比较：随机对照试验

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Objective. The aim of this study was to investigate the difference of efficacy between conventional moxibustion (CM) and smoke-free moxibustion (SM) for patients with osteoarthritis of the knee (KOA). Methods. This is a multicentre, randomized, single blinded, parallel-group clinical trial. Patients with KOA were randomly allocated to CM group (69) and SM group (69) in 7 hospitals of China. Moxibustion treatment in 12 sessions over 4 weeks was administrated at 3 acupuncture points (EX-LE4, ST35, and ST36). Patients completed standard questionnaires at baseline and after 2 weeks, 4 weeks, 8 weeks, and 12 weeks. The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) from the baseline to 4 weeks. The secondary outcomes include Visual Analogue Scale (VAS) and Patient Global Assessment score (PGA). Results. Analyses showed that the WOMAC score improved in pain (95% CI,-0.1[-1.2 to 0.9], p=0.76), stiffness (95% CI,-0.1 [-0.5 to 0.3], p=0.71), and function (95% CI, 2.2 [-1.3 to 5.8], p=0.22) compared between the two groups at 4 weeks, as well as the VAS score (95% CI,0.1 [-0.3 to 0.6], p=0.60). Similar results presented at 8 and 12 weeks. No statistically significant difference was observed between CM and SM groups for outcome measurements. Conclusions. It suggested that smoke generated during moxibustion treatment does not affect the efficacy of moxibustion in the treatment of KOA, which should be taken into account to be removed for the sake of reducing environmental pollution or moxa smoke exposure of acupuncturists or patients. This trial is registered with Clinical Trials.gov, NCT02772055.
机译：客观的。本研究的目的是探讨患有膝关节骨关节炎患者的常规艾灸（CM）和无烟艾灸（SM）之间的疗效差异（KOA）。方法。这是一种多期，随机，单一盲，并联群临床试验。 KOA患者随机分配给CM组（69）和SM组（69）的中国医院。在3个针灸点（EX-LE4，ST35和ST36）上给药12周内12个课程中的艾灸治疗。患者在基线完成标准问卷，2周，4周，8周和12周后。主要结果是西安大略省和麦克马斯特大学骨关节炎指数（Womac）从基线到4周。二次结果包括视觉模拟量表（VAS）和患者全局评估评分（PGA）。结果。分析表明，WOMAC得分在疼痛中改善（95％CI，-0.1 [-1.2至0.9]，P = 0.76），刚度（95％CI，-0.1 [-0.5至0.3]，P = 0.71）和功能（95％CI，2.2 [-1.3至5.8]，p = 0.22）在4周内比较两组，以及VAS得分（95％CI，0.1 [-0.3至0.6]，P = 0.60）。类似的结果在8和12周呈现。在CM和SM组之间没有观察到统计学上显着的差异进行结果测量。结论。它表明，在艾灸治疗期间产生的烟雾不会影响艾灸治疗KOA的疗效，这应该被考虑在减少穴位或患者的环境污染或MOXA烟雾暴露时被移除。该试验在临床试验中注册.GOV，NCT02772055。

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