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Genome-wide differential expression of long noncoding RNAs and mRNAs in ovarian follicles of two different chicken breeds

机译:两种不同鸡品种卵巢卵泡卵巢卵巢和mRNA的基因组差异表达

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Bashang long-tail chickens are an indigenous breed with dual purpose in China (meat and eggs) but have low egg laying performance. To improve the low egg laying performance, a genome-wide analysis of mRNAs and long noncoding RNAs (lncRNAs) from Bashang long-tail chickens and Hy-Line brown layers was performed. A total of 16,354 mRNAs and 8691 lncRNAs were obtained from ovarian follicles. Between the breeds, 160 mRNAs and 550 lncRNAs were found to be significantly differentially expressed. Integrated network analysis suggested some differentially expressed genes were involved in ovarian follicular development through oocyte meiosis, progesterone-mediated oocyte maturation, and cell cycle. The impact of lncRNAs on cis and trans target genes, indicating some lncRNAs may play important roles in ovarian follicular development. The current results provided a catalog of chicken ovarian follicular lncRNAs and genes for further study to understand their roles in regulation of egg laying performance.
机译:Bashang Long-Tail Chickens是中国的土着品种,在中国(肉类和鸡蛋),但具有较低的鸡蛋铺设性能。为了提高低卵铺设性能,进行MRNA的基因组分析和来自Bashang长尾鸡和Hy-Line棕色层的MRNA和长的NONCODING RNA(LNCRNA)。从卵巢卵泡中获得总共16,354 mRNA和8691克朗。发现品种,160mRNA和550克尔氏菌属显着表达。综合网络分析表明一些差异表达的基因通过卵母细胞减数分裂,孕酮介导的卵母细胞成熟和细胞周期参与卵巢卵泡发育。 LNCRNA对CIS和反式靶基因的影响,表明一些LNCRNA可能在卵巢卵泡发育中起重要作用。目前的结果提供了鸡卵巢卵泡LNCRNA和基因目录,以进一步研究,以了解其作用在调节卵子铺设性能方面。

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