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MicroRNA-related markers associated with corpus luteum tropism in buffalo (Bubalus bubalis)

机译：与Corpus Luteum Tropism相关的MicroRNA相关标记（Bubalus Bubalis）

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The study was undertaken to decipher the microRNA (miRNA) related markers associated with corpus luteum (CL) tropism in buffalo. The data obtained from deep sequencing of CL tissue from different physiological stages was mined in silico for the identification of miRNA-related markers (SSR & SNP). From the present study, 5 annotated and 176 unannotated miRNA were deduced while comparing with Bos taurus genome. In addition, 4 SSRs and 9 SNPs were deduced from the miRNA sequences. These SSRs were on the genes viz. Eukaryotic translation initiation factor 1-like, myocyte enhancer factor 2A, beta casein, T cell receptor gamma cluster 1. The SNP positions on genes viz. PYGO1 (Pygopus family PHD finger 1), LOC100337244 (Multidrug resistance-associated protein 4), FTH1 (Ferritin heavy chain 1), LOC788634 (BOLA class I histocompatibility antigen), PLXND1 (Plexin D1) and UBC (Ubiquitin C) show that these genes play critical role in CL tropism during estrous cycle in buffalo.
机译：该研究旨在破译与水牛毒素（CL）对抗相关的MicroRNA（miRNA）相关标志物。从不同生理阶段的Cl组织的深度测序获得的数据在硅中进行，用于鉴定MiRNA相关标记物（SSR＆SNP）。从本研究中，与Bos Taurus Genome相比，推导出5个注释和176个未解说的miRNA。此外，从MiRNA序列推导出4SSR和9个SNP。这些SSRS在基因上。真核翻译引发因子1样，肌细胞增强剂因子2a，β酪蛋白，t细胞受体γ簇1. viz基因上的SNP位置。 pygo1（Pygopu​​s家族博士1），LOM100337244（多药抗性相关蛋白4），Fth1（铁蛋白重链1），LOM788634（Bola类I组织代表性抗原），PLXND1（Plexin D1）和UBC（泛素C）表明这些基因在水牛口修饰循环期间在Cl Trophis中发挥着关键作用。

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