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Identification of Arabis alpina genomic regions associated with climatic variables along an elevation gradient through whole genome scan

机译：通过全基因组扫描鉴定与高程梯度沿高程梯度相关的阿拉伯阿尔皮纳基因组区域

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We performed a pooled whole-genome sequencing on samples of the alpine plant Arabis alpina, harvested in ten populations along an elevation gradient in the French Alps. A large dataset of genetic variations was produced as single nucleotide polymorphisms (SNPs). A combined genome scan approach enabled detecting genomic regions associated with a synthetic environmental variable characterizing the climate at each sampling location. Positive loci detected by two methods were retained and belong to 19 regions in the Arabis alpina genome. The most significant region harbors an ortholog of the AtNAC062 gene, encoding a membrane-bound transcription factor described as linking the cold response and pathogen resistance that may confer protection to plants under extended snow coverage at high elevations. Other genes involved in the stress response or in flowering regulation were also detected. Altogether, our results indicated that Arabis alpina represent a suitable model for studying genomic adaptation in alpine perennial plants.
机译：我们对阿尔卑斯植物阿拉伯阿拉伯阿拉伯的样品进行了汇集的全基因组测序，沿着法国阿尔卑斯山的海拔梯度收获了10个群体。产生大型遗传变异数据集作为单核苷酸多态性（SNP）。组合基因组扫描方法使能检测与合成环境变量相关的基因组区域，其特征在每个采样位置处的气候。通过两种方法检测到的阳性基因座，并属于阿拉伯阿尔皮纳基因组中的19个区域。最重要的区域患有atnac062基因的正牙，编码被描述为连接冷响应和病原体抗性的膜结合转录因子，该转录因子可以在高升高的延长的雪覆盖下赋予植物的植物。还检测了参与应力反应或开花调节的其他基因。完全，我们的结果表明Arabis Alpina代表了在高症常年植物中研究基因组适应的合适模型。

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