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Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast

机译:染色质重塑复合物涉及在发芽酵母静态发酵过程中调节乙醇生产

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The budding yeast Saccharomyces cerevisiae remains a central position among biofuel-producing organisms. However, the gene expression regulatory networks behind the ethanol fermentation is still not fully understood. Using a static fermentation model, we have examined the ethanol yields on biomass of deletion mutants for all yeast nonessential genes encoding transcription factors and their related proteins in the yeast genome. A total of 20 (about 10%) transcription factors are identified to be regulators of ethanol production during fermentation. These transcription factors are mainly involved in cell cycling, chromatin remodeling, transcription, stress response, protein synthesis and lipid synthesis. Our data provides a basis for further understanding mechanisms regulating ethanol production in budding yeast.
机译:萌芽酵母酿酒酵母遗骸仍然是生物燃料生物体中的中心位置。然而,乙醇发酵后面的基因表达调节网络仍未完全理解。使用静态发酵模型,我们研究了对酵母基因组中的所有酵母非子基因的乙醇产量对缺失突变体的生物量及其相关蛋白质中的酵母基因组。总共20个(约10%)转录因子被鉴定为在发酵过程中是乙醇生产的调节因子。这些转录因子主要涉及细胞循环,染色质重塑,转录,应力反应,蛋白质合成和脂质合成。我们的数据为进一步了解调节培养酵母乙醇生产的机制提供了基础。

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