Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell Cycle-Associated Proteins

Joseph Kim; Brendan McKeown; Kunal Patel; Adriana Catalli; Marianna Kulka; Catherine Neto; Robert Hurta

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Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell Cycle-Associated Proteins

机译：来自美国蔓越莓（丙啶Macrocarpon）的原花青素通过影响细胞周期相关蛋白的表达，在体外诱导Du145人前列腺癌细胞的细胞周期改变

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Background: Prostate cancer is one of the most common cancers in the world. There are genetic and environmental factors that can potentially impact the development and progression of many types of cancer, including prostate cancer. As a consequence of environmental factors, such as diet having a potential effect on the development of prostate cancer, considerable interest in the possible health benefits associated with the inclusion and consumption of certain foods in the diet exists.

机译：背景：前列腺癌是世界上最常见的癌症之一。存在遗传和环境因素，可能会影响许多类型癌症的发展和进展，包括前列腺癌。由于环境因素的结果，例如对前列腺癌的发展具有潜在影响的饮食，对饮食中包含和消耗某些食物的可能健康益处具有相当大的兴趣。

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《Functional Foods In Health And Disease》 |2014年第4期|共17页
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Joseph Kim; Brendan McKeown; Kunal Patel; Adriana Catalli; Marianna Kulka; Catherine Neto; Robert Hurta;
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1. Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways. [J] . Deziel BA, Patel K, Neto C, Journal of cellular biochemistry. . 2010,第3期

机译：来自美洲蔓越莓的原花色素（Vaccinium macrocarpon）通过多种细胞信号传导途径的改变抑制人前列腺癌细胞中的基质金属蛋白酶2和基质金属蛋白酶9活性。
2. North American Cranberry (Vaccinium Macrocarpon) Stimulates Apoptotic Pathways in DU145 Human Prostate Cancer Cells In Vitro [J] . Malcolm A. MacLeana Bradley E. Scotta Bob A. Deziela Melissa C. Nunnelleyb Anne M. Libertyb Katherine T. Gottschall-Passc Catherine C. Netob Robert A. R. Hurtaa Nutrition and Cancer . 2011,第1期

机译：北美蔓越莓（Vaccinium Macrocarpon）体外刺激DU145人前列腺癌细胞的凋亡途径。
3. North American cranberry (Vaccinium macrocarpon) stimulates apoptotic pathways in DU145 human prostate cancer cells in vitro. [J] . MacLean MA, Scott BE, Deziel BA, Nutrition and Cancer: An International Journal . 2011,第1期

机译：北美蔓越莓（Vaccinium macrocarpon）在体外刺激DU145人前列腺癌细胞中的凋亡途径。
4. Panoxadiol saponin enhances apoptotic effect of cisplatin on DU145 prostatic cancer cells [C] . Yanbo Liu, Lili Lu, Weigao Shen, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：Panoxadiol皂苷可增强顺铂对DU145前列腺癌细胞的凋亡作用
5. Effect of citrus bioflavonoids naringenin and hesperetin on hormone-insensitive human prostate cancer DU145 cells. [D] . Patani, Radhika. 2007

机译：柑橘类生物类黄酮柚皮素和橙皮素对激素不敏感的人前列腺癌DU145细胞的影响。
6. Knockdown of cell division cycle-associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA-MB-231 cells in vitro and in vivo [O] . Sen Pang, Yuju Xu, Jun Chen, -1

机译：敲低细胞分裂周期相关蛋白4的表达抑制体内和体外三阴性乳腺癌MDA-MB-231细胞的增殖
7. Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell Cycle-Associated Proteins [O] . Joseph Kim, Brendan McKeown, Haris Jahic, 2014

机译：来自美国蔓越莓（Vaccinium macrocarpon）的原花青素通过影响细胞周期相关蛋白的表达诱导DU145人前列腺癌细胞的细胞周期改变

Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell Cycle-Associated Proteins

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