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Immunomodulation for maxillofacial reconstructive surgery

机译:颌面重建手术免疫调节

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Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings.
机译:免疫调节是一种用于调节移植物材料以改善手术成功率的免疫应答的技术。免疫调节的主要靶细胞是巨噬细胞,因为它是移植物的反应位点并控制愈合过程。巨噬细胞可以分为M1和M2类型。大多数免疫调节技术关注M2型巨噬细胞的快速分化。最近已经鉴定了M2诱导剂,4-己基苯乙烯醇,用于骨移植和牙科植入物涂层。

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