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Waddlia chondrophila and Male Infertility

机译：Waddlia chondrophila和男性不孕症

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摘要

Waddlia chondrophila , a Chlamydia -like bacterium, has been previously associated with adverse pregnancy outcomes. Analogously to Chlamydia trachomatis , W. chondrophila also negatively impacts human semen and may be a source of impaired male fertility. In this study, we analyzed W. chondrophila seroprevalence in a population of male patients of infertile couples and the impact of past exposition to this bacterium on semen parameters. Our results show a surprisingly high seroprevalence of W. chondrophila , which contrasts with a previous study focusing on a population of healthy men. Nevertheless, we did not observe any significant association between positive serology and abnormal sperm parameters. This may suggest that a negative impact on semen is observed only during an ongoing infection. Alternatively, W. chondrophila may have an immune impact on male fertility, as previously postulated for women with adverse pregnancy outcomes.
机译：Waddlia chondrophila是一种衣原体，衣物状细菌，先前已与不良妊娠结果相关。类似于Chlamydia Thramomatis，W.Chondrophila也对人类精液产生负面影响，并且可能是男性生育能力受损的来源。在这项研究中，我们分析了在患有不孕夫妇患者的患者中的W.Chondrophila Seroprengence以及过去博览会对该细菌的影响。我们的结果表明，W.Chondrophila的令人惊讶的高血清伪装，其与以前的研究对比重点是健康人群。然而，我们没有观察到阳性血清学和异常精子参数之间的任何重大关联。这可能表明在持续的感染期间仅观察到对精液的负面影响。或者，W.Chondrophila可能对男性生育的免疫影响，如先前为具有不良妊娠结果的妇女假定。

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