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首页> 外文期刊>Reproductive Health >Comparative study in infertile couples with and without Chlamydia trachomatis genital infection
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Comparative study in infertile couples with and without Chlamydia trachomatis genital infection

机译：不含衣原体衣原体生殖器感染的不孕夫妇的比较研究

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Background Chlamydia , caused by the bacterium Chlamydia trachomatis(C. trachomatis) , is the most common sexually transmitted disease. The incidence is not clear due to the asymptomatic nature of early stage of infections. The incidence of Chlamydia has not been fully investigated in the Chinese Han population. Since chronic infection with can C. trachomatis can lead to infertility in males and females, it is important to determine the impact of infection on clinical outcomes. The aim of this study is to explore the epidemiology of C. trachomatis in subfertile couples and to determine whether infections will adversely affect clinical outcomes after assisted reproduction technique (ART) treatment. Methods Subfertile patients ( n =?30760) were screened in the research for C. trachomatis in our center from January 2010 to December 2014. C. trachomatis -specific DNA was detected by Taq-man PCR from semen or swabs from the urethral, endocervix or vaginal. The control group consisted of 1140 subfertile patients without C. trachomatis infection. The prevalence and characteristics of C. trachomatis were identified for subfertile couples and clinical outcomes were collected and analyzed. A retrospective study was performed. Results Nine hundred and seventy patients were diagnosed with C. trachomatis infection, and the overall prevalence was 3.15% in the most recent five years, with a yearly increasing. The incidence was a higher in the second half of the year (3.40%) compared to the first half (2.69%). The age group with the highest-risk of infection with C. trachomatis was between 26 to 35?years old, and in about one third of the couples, both partners were infected. The basic parameters and clinical outcomes were not statistically significant between different the groups ( P >?0.05), even though some minor data were different ( P Conclusions C. trachomatis is a common infection in subfertile people and it is essential to test for this organism in ART couples’ screening. This study identified no adverse on clinical outcomes after successful treatment of C. trachomatis infection, regardless of gender, age and number of C. trachomatis copies.
机译：背景衣原体，由细菌衣原体衣原体（C.Trachomatis）引起的，是最常见的性传播疾病。由于感染的早期阶段的无症状，发病率尚不清楚。中国汉族人口尚未全面调查衣原体的发病率。由于慢性感染Cas C. Thachomatis可以导致男性和女性中的不孕症，因此确定感染对临床结果的影响是重要的。本研究的目的是探讨在辅助夫妇中的C. Thachomatis的流行病学，并确定感染是否会对辅助生殖技术（艺术）治疗后的临床结果产生不利影响。方法在2010年1月至2014年12月，在我们的中心C. Thachomatis的研究中筛选了筛选患者或阴道。对照组包括1140名没有C.颅摩擦感染的患者。鉴定了C. Thachomatis的患病率和特征，并收集了临床结果并分析了临床结果。进行了回顾性研究。结果九百七十名患者被诊断为C. Thachomatis感染，最近五年的整体流行率为3.15％，每年增加。与上半年（2.69％）相比，该年下半年的发病率较高（3.40％）。该年龄组具有最高风险的感染C. Thachomatis的年龄在26至35岁之间，并且在大约三分之一的夫妻中，两个合作伙伴都被感染了。基本参数和临床结果在不同的组之间没有统计学意义（p> 0.05），即使一些次要数据不同在艺术夫妻的筛选中。本研究确定了在成功治疗C. Thachomatis感染后的临床结果没有任何不利，无论性别，年龄和C. Thachomatis副本。

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