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The Ability to Visually Recognize Facial Emotions during the Initial Stages of Alzheimer’s

机译:在Alzheimer的初始阶段视觉上识别面部情绪的能力

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Background : Alzheimer’s sufferers (AS) are unable to visually recognize facial emotions (VRFE). However, we do not know the kind of emotions involved, the timeline for the onset of this loss of ability to recognize facial emotional expressions during the natural course of this disease and the existence of any correlation with other comorbid cognitive disorders. For that reason, the authors aimed to determine whether a deficit in facial emotion recognition is present at the onset of Alzheimer disease, distinctly and concurrently with the onset of cognitive impairment or is it a prodromal syndrome of Alzheimer’s Disease before the onset of cognitive decline and what emotions are involved. A secondary aim was to investigate relationships between facial emotion recognition and cognitive performance on various parameters. Method: Single Blind Case-control study. Setting in Memory clinic. Participants: 12 patients, (AS) and 12 control subjects (CS) were enrolled. Measurements: Quantitative information about the ability for facial emotion recognition was obtained from Method of Analysis and Research on the Integration of Emotions (MARIE). The Mini Mental Status Examination (MMSE), the Picture Naming, the Mattis Dementia Rating Scale (DRS), and the Grober & Buschke Free and Cued Selective Reminding Test (FCSRT) tests were used to measure cognitive impairment. Results: We note that the AS have a problem with the visual recognition of facial emotions with existence of a higher threshold for visual recognition. The AS is less sensitive to the visual recognition cues of facial emotions. AS is unable to distinguish anger from fear. It would be a possible explanation for some acts of aggressiveness seen in the clinical and home setting demonstrated by “AS with behavioral disturbance ”. The anger-fear series was found to be the first affected in the course of Alzheimer’s. The appearance of the curve is sigmoid for the control group and linear for the Alzheimer’s patients with a cognitive distortion when the VRFE is represented graphically with percentage of correct recognition plotted on the “y” axis and the selected images presented as stimulus with measures of density of emotion plotted on the “x” axis. In both groups, it is intuitively and theoretically expected that correct recognition will be directly proportional to the density of represented emotion in the stimulus image. This hypothesis is true for CS but not so for AS. The MARIE (see below ) processing of emotions seems to be strengthened by the optimal cognitive functions showing the hypothesis applies to CS but not uniformly in AS. This anomaly in the AS is evidenced by the decline of the cognitive functions contributing to abovementioned “linearization” in the graphic representation. There is a direct positive correlation between the results of MARIE and the performance on cognitive tests. Conclusion: The administration of a combination of DRS, FCSRT, and MARIE to patients screened for possibly emerging Alzheimer’s could provide a more detailed and specific approach to make a definitive early diagnosis of Alzheimer’s. The Alzheimer’s patients found it difficult to distinguish between anger and fear.
机译:背景:阿尔茨海默氏症的患者(AS)无法视觉上识别面部情绪(VRFE)。然而,我们不知道这种情感的情感,这种丧失这种疾病自然过程中面部情绪表达的能力的时间表以及与其他同血管认知障碍的任何相关性的能力。因此,作者旨在确定面部情感识别的缺陷是在阿尔茨海默病的发作,明显和同时在认知障碍的发作中存在,或者是阿尔茨海默病的前驱疾病在认知下降之前涉及什么情绪。二次目的是调查各种参数对面部情感识别和认知性能之间的关系。方法:单一盲案控制研究。设置在内存诊所。参与者:12名患者(AS)和12名对照受试者(CS)均被纳入。测量:从情绪融合的分析和研究方法获得了关于面部情感识别能力的定量信息。迷你精神状态检查(MMSE),图片命名,Mattis Dementia评级规模(DRS)以及GREBER&BUSCHKE免费和CURE选择性提醒测试(FCSRT)测试用于测量认知障碍。结果:我们注意到,由于视觉识别面部情绪的视觉识别存在较高的视觉识别阈值的问题。对面部情绪的视觉识别提示的视觉识别提示的敏感性不太敏感。因为无法与恐惧区分愤怒。在“与行为干扰一样”的临床和家庭环境中,对某些侵略性行为的可能解释是一个可能的解释。愤怒的恐惧系列被发现是阿尔茨海默氏症过程中的第一次受影响。曲线的外观是对照组的SIGMOID,并且当VRFE以绘制在“Y”轴上的正确识别百分比以图形表示时,Alzheimer的患者的线性是具有正确识别的百分比,并且所选择的图像与密度呈现为刺激的刺激情绪绘制在“x”轴上。在这两个群体中,它直观地和理论上预期,正确的识别将与刺激图像中所代表的情绪的密度成比例。对于CS而言,这个假设是真的,但不是如此。 Marie(见下文)似乎通过显示假设适用于CS但不统一的最佳认知功能来加强情绪。根据图形表示中有助于上述“线性化”的认知函数的衰落所证明的那种异常所证明。玛丽的结果与认知测试的性能之间存在直接的正相关。结论:给予患者筛选的患者组合的给药,以筛选的患者可能提供更详细和具体的方法,以实现阿尔茨海默氏症的最终诊断。阿尔茨海默氏症的患者发现很难区分愤怒和恐惧。

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