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首页> 外文期刊>Ophthalmology and therapy. >A Review of Macular Atrophy of the Retinal Pigment Epithelium in Patients with Neovascular Age-Related Macular Degeneration: What is the Link? Part II
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A Review of Macular Atrophy of the Retinal Pigment Epithelium in Patients with Neovascular Age-Related Macular Degeneration: What is the Link? Part II

机译：对新生血管年龄相关性黄斑变性患者视网膜色素上皮的黄斑萎缩述评：链接是什么？第二部分

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IntroductionTo explore the potential link between macular atrophy (MA) of the retinal pigment epithelium (RPE) in patients with neovascular age-related macular degeneration (nAMD) and anti-vascular endothelial growth factor (anti-VEGF) treatment.MethodsThrough a balanced overview of the field from a largely clinical perspective, we looked at available evidence on the topic of MA correlation with anti-VEGF therapy and examined possible risk factors for MA development in the context of nAMD treatment with anti-VEGF.ResultsLinks have been reported to connect both MA incidence and progression to treatment frequency and to the anti-VEGF drug type.ConclusionsAll reports agree on the fact that de novo development of MA in anti-VEGF-treated eyes is frequent and multifactorial. Research data shows an expansion of atrophy during anti-VEGF treatment. There are mixed conclusions about the correlation of MA incidence or progression with treatment-related risk factors. It mostly appears that there is no straightforward link. More clinical research is still needed to further understand this association.
机译：介绍探讨患有新生血管年龄相关性黄斑（NamD）和抗血管内皮生长因子（抗VEGF）治疗患者视网膜色素上皮细胞（RPE）的黄斑色素上皮（RPE）之间的潜在联系。一般概述该领域从一个很大程度上的临床角度来看，我们看了关于抗VEGF治疗的MA相关话题的可用证据，并据报道，在NAMD治疗的情况下，据报道，据据报道，据据报道，据据报道，据据报道了两个MA发病率和进展到治疗频率和抗VEGF药物类型。链接载体的报告达成协议，即抗VEGF治疗眼中的MA Novo开发是频繁和多重的。研究数据显示抗VEGF处理期间萎缩的扩张。关于与治疗相关的危险因素的母发病或进展的相关性的结论。它主要似乎没有简单的链接。仍然需要更多的临床研究来进一步了解这一协会。

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