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首页> 外文期刊>Orthopaedic Journal of Sports Medicine >Patients With Abnormal Limb Kinetics at 6 Months After Anterior Cruciate Ligament Reconstruction Have an Increased Risk of Persistent Medial Meniscal Abnormality at 3 Years
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Patients With Abnormal Limb Kinetics at 6 Months After Anterior Cruciate Ligament Reconstruction Have an Increased Risk of Persistent Medial Meniscal Abnormality at 3 Years

机译：肢体动力学异常在6个月后6个月患者在3年内增加了持续内侧半月岩异常的风险增加

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Background: Several reports have shown that altered biomechanics after anterior cruciate ligament reconstruction (ACLR) are associated with the development of posttraumatic osteoarthritis. However, it is not fully understood whether altered biomechanics are associated with meniscal changes after ACLR. Purpose: To investigate changes in gait and landing biomechanics over a 3-year period and their correlation with meniscal matrix alterations present before and after ACLR through use of magnetic resonance T1ρ/T2 mapping, which can allow detection of early meniscal degeneration. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 36 patients with ACLR and 14 healthy controls were included in this study. All patients underwent magnetic resonance imaging and biomechanical analysis during gait of the injured knee and contralateral knee preoperatively and at 6 months, 1 year, 2 years, and 3 years after ACLR, as well as biomechanical analysis during drop-landing from 6 months to 3 years postoperatively. To evaluate biochemical changes of the mensical matrix, T1ρ/T2 relaxation times of the meniscus were calculated. Results: Mean T1ρ/T2 values of ACLR knees were significantly higher than values in the contralateral and control knees in the posterior lateral and medial horns up to 1 year after surgery; however, the differences were not seen at 3 years after surgery. The ACLR knee exhibited significantly lower peak knee flexion moment and angle during gait at 6 months compared with baseline and continued to decrease until 3 years. The ACLR knee exhibited significantly lower peak vertical ground-reaction force and peak knee flexion moment and angle during landing at 6 months. However, the differences were no longer present at 3 years. Biomechanics at 6 months had significant correlations with changes of mean T1ρ/T2 values in the medial posterior horn from 6 months to 3 years after ACLR. Conclusion: Although mean T1ρ/T2 values of meniscus seen before ACLR improved after 3 years, approximately 30% of patients with ACLR did not show decreases from 6 months to 3 years. Patients with abnormal lower limb kinetics of the ACLR knee at 6 months showed less recovery in the medial posterior horn from 6 months to 3 years, suggesting that biomechanical parameters during the early stage of recovery might be potential biomarkers for predicting persistent medial meniscal abnormality after ACLR.
机译：背景：几个报告表明，前十字韧带重建（ACLR）发生改变的生物力学与术后骨关节炎的发展有关。然而，尚不完全明白改变的生物力学与ACLR后的半月板变化有关。目的：通过使用磁共振T1ρ/ T2映射，调查3年期间的步态和降落生物力学的变化及其与ACLR之前和之后的半月板基质改变的相关性，这可以允许检测早期半月板变性。研究设计：队列研究;证据水平，2.方法：本研究中共有36例ACLR和14例健康对照。所有患者在术前和对侧膝关节的步态和6个月，1年，2岁和3年后，所有患者接受磁共振成像和生物力学分析，以及在ACLR后的3年，以及从6个月到3的降落期间的生物力学分析多年术后。为了评估语言基质的生化变化，计算弯月面的T1ρ/ T2弛豫时间。结果：手术后1年后，ACLR膝盖的平均T1ρ/ T2值显着高于后侧和内侧角度的对侧和控制膝盖的值;然而，手术后3年没有看到差异。与基线相比，ACLR膝关节显示在步态期间显着降低高峰膝关节弯矩和角度，并继续降低至3年。 ACLR膝关节在6个月内呈现显着降低峰值垂直地反作用力和峰值膝关节弯曲力矩和角度。但是，3年不再存在差异。 6个月的生物力学与ACLR后6个月至3年后内侧后角的平均t1ρ/ t2值的变化具有显着相关性。结论：虽然ACLR在3年后改善之前的平均T1ρ/ T2值，但大约30％的ACLR患者没有显示出6个月至3年。患有6个月的ACLR膝关节异常的患者在6个月内显示出少6个月至3年的中喇叭较少，表明在恢复早期期间的生物力学参数可能是用于预测ACLR后持续内侧半月岩异常的潜在生物标志物。

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