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首页> 外文期刊>Sao Paulo Medical Journal >Quality of life among patients with age-related severe macular degeneration assessed using the NEI-VFQ, HADS-A, HADS-D and SF-36 tests. A cross-sectional study
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Quality of life among patients with age-related severe macular degeneration assessed using the NEI-VFQ, HADS-A, HADS-D and SF-36 tests. A cross-sectional study

机译：使用Nei-VFQ的年龄相关的严重黄斑变性患者的生活质量患者，HADS-A，HATS-D和SF-36测试。横断面研究

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BACKGROUND: Exudative age-related macular degeneration (e-AMD) may cause severe central vision loss. Patients with e-AMD can experience difficulties in daily basic activities and suffer from psychological problems. Our aim was to assess quality of life (QoL) and anxiety and depression status among patients with e-AMD. DESIGN AND SETTING: Cross-sectional study in a state university. METHODS: We included 200 e-AMD patients and 120 age and gender-matched controls. We assessed QoL using the National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25) and the Short Form (SF)-36 test; and anxiety and depression status using the Hospital Anxiety Depression Scales A and D (HADS-A and HADS-D). RESULTS: The mean ages in the e-AMD and control groups were 68.40 ± 9.8 and 66.31 ± 8.98, respectively. Visual acuity among e-AMD patients was 0.37 ± 0.31 and 0.39 ± 0.32 in the right and left eyes, respectively. The e-AMD patients performed significantly worse than the controls in NEI-VFQ-25 (P 0.05 for all items). The proportions of e-AMD patients scoring higher than the cutoffs in HADS-A and HADS-D were significantly higher than among the controls (41.5% versus 12.5% and 63.5% versus 27.5%; P 0.001). The e-AMD patients had significantly lower mean scores than the controls for each of the SF-36 QoL items (P 0.001). The NEI-VFQ-25 scores were significantly lower among patients with bilateral e-AMD than among those with unilateral disease (P 0.05 for all). The HADS scores were positively correlated with duration of e-AMD and patient age, but negatively with vision levels (P 0.05 for all items). CONCLUSION: The e-AMD patients had higher depression and anxiety scores and lower QoL scores.
机译：背景：渗出性年龄相关的黄斑变性（E-AMD）可能导致严重的中央视力丧失。 E-AMD患者可以在日常基本活动中遇到困难并遭受心理问题。我们的目标是评估E-AMD患者的生活质量（QOL）和焦虑和抑郁状况。设计与环境：国家大学的跨剖面研究。方法：我们包括200名E-AMD患者和120名年龄和性别匹配的对照。我们使用国家眼部学院视觉运作问卷-25（Nei-VFQ-25）和短型（SF）-36测试进行评估QoL;使用医院焦虑抑郁尺度A和D（HADS-A和HADS-D）的焦虑和抑郁状态。结果：E-AMD和对照组的平均年龄分别为68.40±9.8和66.31±8.98。 E-AMD患者之间的视力分别在右眼和左眼中为0.37±0.31和0.39±0.32。 E-AMD患者比NEI-VFQ-25中的对照显着差（所有物品P <0.05）。 e-amd患者的比例高于HS-A和HATS-D的截止值显着高于对照组（41.5％而与12.5％和63.5％相比; P <0.001）。 E-AMD患者的平均分数明显低于每种SF-36 QOL项目的对照（P <0.001）。双侧E-AMD患者的NEI-VFQ-25分数显着低于单侧疾病的患者（P <0.05）。与E-AMD持续时间和患者年龄的持续时间呈正相关，但对视觉水平负面呈负相关（所有物品的P <0.05）。结论：E-AMD患者的抑郁症和焦虑分数较高，QOL分数降低。

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