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首页> 外文期刊>Saudi Pharmaceutical Journal >Awareness among patient at risk of developing Medication Related Osteonecrosis of the Jaw (MRONJ) – A primary prevention strategy
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Awareness among patient at risk of developing Medication Related Osteonecrosis of the Jaw (MRONJ) – A primary prevention strategy

机译：患者在患有颌骨相关骨折的患者患者的意识（mronj） - 初级预防策略

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摘要

The quality of life, in itself, in cancer patients or in osteoporotic individuals, without even considering the side effects of the medication in the first place, has a considerable negative impact on the clinical outcome. The Medication Related Osteonecrosis of the Jaw (MRONJ), in the maxillofacial region, although rare, needs to be addressed with the prime importance. One of the key components of any given preventive treatment strategy is to, create awareness about the medication related unwanted effects, among health care professionals and patients. Objective This study is aimed to explore and assess the awareness level among dental patients about MRONJ, the risk factors, and the high-risk category (who are prone to develop MRONJ). Material and methods This is a prospective interviewer administered research electronic data capture (REDCap) survey. The sample included 68 patients, who are currently taking or will be taking Bisphosphonate (BP), and/or Denosumab, and anti-Angiogenic agent. Data have been analyzed using IBM SPSS software, Results Sixty-eight patients (18 males and 50 females), participated in this study. Only 23 subjects (33.82%) were aware about the MRONJ. Females were more aware about the complications than males. The awareness among the subjects with education at college level appears to be higher than the subjects having education less than high school level. Even though, a dental check- up, is mandatory, prior to starting these medications, to see if any dental treatment is required, only slightly more than half of the patients (54.72%) had a dental checkup. Conclusion This is a novel study in the Middle- East, used to assess awareness about the MRONJ including three type of related medications. Low awareness of MRONJ is alarming. The results of the study will help to initiate the process of providing the education materials, about the side effects and importance of oral hygiene maintenance, giving priority to improve the quality of life in such patients. Awareness of patients regarding the complications must be an important part of health care practice guidelines.
机译：生活质量，本身，在癌症患者或骨质疏松患者中，甚至不考虑药物的副作用，对临床结果具有相当大的影响。在颌面区域的颌面区域中的颌骨（mronj）的药物相关osteonecrys需要以罕见的重要性来解决。任何给定的预防性治疗策略的关键部件之一是，在医疗保健专业人员和患者中创造有关药物相关的药物相关性效应的认识。目的本研究旨在探讨和评估牙科患者关于Mronj，风险因素和高风险类别的意识水平（易于发展Mronj）。材料和方法这是一个潜在的面试官，管理研究电子数据捕获（Redcap）调查。该样品包括目前服用的68名患者，或将服用双膦酸酯（BP）和/或DeaOnaMab和抗血管生成剂。使用IBM SPSS软件分析了数据，结果68名患者（18名男性和50名女性），参加了这项研究。只有23个科目（33.82％）了解mronj。女性更加了解并发症比男性的并发症。大学教育受试者的认识似乎高于教育低于高中级别的主题。尽管在开始这些药物之前，牙科检查是强制性的，但要看看是否需要任何牙科治疗，只有略微超过一半的患者（54.72％）患有牙科检查。结论这是中东地区的一种新型研究，用于评估关于Mronj的意识，包括三种类型的相关药物。低意识mronj是令人担忧的。该研究的结果将有助于提起提供教育材料的过程，了解口腔卫生维护的副作用和重要性，优先提高这些患者的生活质量。关于并发症的患者的认识必须是医疗保健实践指南的重要组成部分。

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