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In-Hospital Mortality among Ischemic Stroke Patients in Gondar University Hospital: A Retrospective Cohort Study

机译:渡墩大学医院缺血性脑卒中患者的住院死亡率:回顾性队列研究

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Introduction. Ischemic stroke is the third leading cause of mortality in low-income countries and the sixth in Ethiopia. The aim of this study was to determine the rate and predictors of in-hospital mortality due to ischemic stroke in Gondar University Hospital. Methods. The study was conducted from April 1, 2017, to May 15, 2017, at Gondar University Hospital. A census using retrospective cohort study design was conducted on medical records of adult patients with the diagnosis of ischemic stroke attending the medical inpatient ward of Gondar University Hospital between November 2012 and September 2016. Cox hazard regression was used to determine the predictors of in-hospital mortality. A two-sided statistical test at 5% level of significance was used. Results. The mean (±SD) duration of hospital stay was 11.55 (10.040) days. Of the total 208 patients, 26 (12.5%) patients died in the hospital. Cox regression revealed that only a decrease in renal function, particularly elevated serum creatinine (AHR=8.848, 95% CI: 1.616-67.437), was associated with a statistically significant increase of in-hospital mortality. The symptom onset-to-admission time varied greatly among patients and ranged from 1 hour to 168 hours. Conclusion. The in-hospital mortality associated with ischemic stroke was found to be high. Mainly, elevation in serum creatinine was highly associated with poorer outcomes in terms of in-hospital mortality. Much work should be done on improving the knowledge and awareness of the community regarding ischemic stroke and stroke in general to encourage early medical seeking behavior and reduce mortality and long-term disability.
机译:介绍。缺血性中风是低收入国家和埃塞俄比亚的第六个死亡率的第三个主要原因。本研究的目的是确定由于渡戈尔大学医院缺血性脑卒中因医院内死亡率的速率和预测。方法。该研究于2017年4月1日至2017年5月15日,在渡戈尔大学医院。使用回顾性队列研究设计的人口普查对成人患者的病历进行了诊断,诊断缺血性脑卒中的诊断2012年11月至2016年9月期间的潘纳大学医疗病房。COX危险回归用于确定入院的预测因素死亡。使用双面统计测试5%的显着性。结果。住院住院的平均值(±SD)是11.55(10.040)天。在208例患者中,26例(12.5%)患者在医院死亡。 COX回归显示,肾功能下降,特别是血清肌酐(AHR = 8.848,95%CI:1.616-67.437)的降低与患上的内部死亡率增加有关。症状到入院时间在患者中有大量变化,而且从1小时到168小时。结论。发现与缺血性卒中相关的医院内死亡率很高。主要是,在院内死亡率方面,血清肌酐的升高与较差的结果高。应在提高社区的知识和意识方面对缺血性卒中的知识和意识进行大量工作,一般鼓励早期医疗寻求行为,减少死亡率和长期残疾。

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