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首页> 外文期刊>Systematic Reviews >What is the effectiveness of various invitation methods to a colonoscopy in the early detection and prevention of colorectal cancer? Protocol of a systematic review
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What is the effectiveness of various invitation methods to a colonoscopy in the early detection and prevention of colorectal cancer? Protocol of a systematic review

机译：在早期检测和预防结直肠癌中，各种邀请方法对结肠镜检查的有效性是什么？系统审查协议

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Colorectal cancer, a prevalent malignancy worldwide, is associated with numerous modifiable and non-modifiable risk factors that play a role in the early detection and successful treatment of cancer. Despite improvements in the availability and quality of screening methods, especially colonoscopy, and the substantial survival benefits of the early detection of colorectal cancer, patient participation remains low due to clinical reasons and patient barriers. Studies around the world have used various methods of invitation in order to promote patient uptake of colonoscopies. The main objective of this systematic review is to analyze the association between certain invitation procedures, the participation in colonoscopies, and important patient outcomes in the early detection and prevention of colorectal cancer. We will systematically search in electronic databases including Medline via PubMed and Ovid, Cumulative Index of Nursing and Allied Health Literature (CINAHL), and the Cochrane Library. All studies will be described in a table of study characteristics with a risk of bias assessment. In addition, two authors will independently rate the overall quality of evidence for the critical outcomes using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) Working Group approach. Discrepancies regarding the inclusion of studies, data extraction, or risk of bias assessment will be resolved independently by one other reviewer. Due to the heterogeneous design of the studies that will be evaluated in this review, synthesizing data from these studies in the form of a meta-analysis may not be possible. In this instance, we can conduct a descriptive synthesis of data from these studies. The results that arise from this systematic review will reflect the influence that various invitation procedures to a colonoscopy have on patient participation in these screenings. Drawing conclusions about the efficiency of various invitation methods to a colonoscopy can provide valuable information to both clinicians and patients and may not only improve future invitation-based patient recruitment to colonoscopy screenings, but also shape guidelines regarding prevention of colorectal cancer.
机译：结肠直肠癌，全世界普遍存在的恶性肿瘤，与许多可修改和不可改变的危险因素有关，可在早期发现和成功治疗癌症中发挥作用。尽管有所改善筛选方法的可用性和质量，特别是结肠镜检查以及早期检测结直肠癌的大量生存益处，但由于临床原因和患者屏障，患者参与仍然很低。世界各地的研究使用了各种邀请方法，以促进患者的结肠镜检查。该系统审查的主要目的是分析某些邀请程序之间的关联，参与结肠镜，以及早期检测和预防结直肠癌的重要患者结果。我们将系统地搜索电子数据库，包括通过PubMed和Ovid，护理累计指数（Cinahl）和Cochrane图书馆的累积指数。所有研究将在研究特征表中描述，具有偏见评估的风险。此外，两位作者将利用建议，评估，发展和评估（等级）工作组方法的评分，独立对关键结果进行独立评价整体证据。关于包含研究，数据提取或偏见评估风险的差异将由其他审稿人独立解决。由于在本次综述中评估的研究的异质设计，可能无法从这些研究中合成来自这些研究的数据。在这种情况下，我们可以从这些研究中对数据进行描述性合成。从这个系统审查产生的结果将反映各种邀请程序对结肠镜检查的影响对患者参与这些筛查。绘制关于结肠镜检查的各种邀请方法的效率的结论可以为临床医生和患者提供有价值的信息，并且不仅可以改善未来的基于邀请的患者募集到结肠透视筛查，而且还可以为预防结肠直肠癌的构成指导。

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