Membrane tether formation from human hepatocytes

Morozova Natalia E.; Vedyaykin Alexey D.; Sabantsev Anton V.; Pobegalov Georgiy E.; Murashov Sergey V.; Khodorkovskii Mikhail A.

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Membrane tether formation from human hepatocytes

机译：来自人肝细胞的膜系环

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For the first time to our knowledge the mechanical properties (membrane tension and apparent viscosity) of human hepatocyte (HepG2 cell line) membranes were measured by membrane tether formation using optical trap. Membrane tension and apparent membrane viscosity were measured to be 40 ± 3 pN and 0.27±0.07 pN·s/μm respectively. The developed procedure can be used to study connections between liver cell membrane mechanics and different factors, including ethanol and drug consumption, aging, pathological processes, etc.

机译：首次了解人肝细胞（HepG2细胞系）膜的机械性能（膜张力和表观粘度）通过使用光学阱通过膜系骨形成测量。测量膜张力和表观膜粘度分别为40±3 pn和0.27±0.07 pn·s /μm。开发的程序可用于研究肝细胞膜力学和不同因素之间的连接，包括乙醇和药物消耗，衰老，病理过程等。

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《St. Petersburg Polytechnic University Journal: Physics and Mathematics》 |2013年第3期|共10页
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Morozova Natalia E.; Vedyaykin Alexey D.; Sabantsev Anton V.; Pobegalov Georgiy E.; Murashov Sergey V.; Khodorkovskii Mikhail A.;
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membrane tether formationoptical trapHEPG2cell membranehepatocytes;

机译：膜系氮化物光学率Traphepg2Cell膜Hepbatocytes;

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1. Membrane-anchored human Rab GTPases directly mediate membrane tethering in vitro Membrane-anchored human Rab GTPases directly mediate membrane tethering in vitro Membrane-anchored human Rab GTPases directly mediate membrane tethering in vitro [J] . Joji Mima, Naoki Tamura Biology Open . 2014,第11期

机译：膜锚定的人Rab GTPases直接介导体外膜栓系膜锚定的人Rab GTPases直接介导体外膜栓系
2. Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes, membrane tethers) in human neutrophils. [J] . Galkina SI, Stadnichuk VI, Molotkovsky JG, Cell adhesion & migration . 2010,第1期

机译：微生物生物碱星形孢菌素诱导人嗜中性粒细胞中形成纳米级的膜小管延伸（细胞因子，膜系链）。
3. Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes, membrane tethers) in human neutrophils [J] . Svetlana I. Galkina, Vladimir I. Stadnichuk, Julian G. Molotkovsky, Cell adhesion & migration . 2010,第1期

机译：微生物生物碱星形孢菌素诱导人类嗜中性粒细胞形成纳米级膜小管延伸（细胞因子，膜系链）
4. Repopulation of diseased mouse liver with rodent and human adult primary hepatocytes and long-term survival of transplanted hepatocytes in the uPA/RAG-2 mouse model [C] . M. DANDRI, M. R. BURDA, J. PETERSEN, International Congress on Thrombosis . 2002

机译：用啮齿动物和人成人原发性肝细胞的患病小鼠肝脏的重新迁移，upA / Rag-2小鼠模型中移植肝细胞的长期存活
5. Membrane tether formation from outer hair cells with optical tweezers. [D] . Li, Zhiwei. 2002

机译：用光学镊子从外毛细胞形成膜系绳。
6. Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes membrane tethers) in human neutrophils [O] . Svetlana I Galkina, Vladimir Stadnichuk, Julian G Molotkovsky, 2010

机译：微生物生物碱星形孢菌素诱导人类嗜中性粒细胞形成纳米级的膜小管延伸（细胞因子膜系链）
7. Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes, membrane tethers) in human neutrophils [O] . Galkina, Svetlana I, Stadnichuk, Vladimir, Molotkovsky, Julian G, 2010

机译：微生物生物碱星形孢菌素诱导人类嗜中性粒细胞形成纳米级的膜小管延伸（细胞因子，膜系链）

Membrane tether formation from human hepatocytes

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